This facility core has been operating under the name of Molecular Biology Facility Service Core since the beginning of the Center in 1993. The name of this Core has been changed at this time of competitive renewal in accordance with the recommendation made by the New Directions Committee. This change is intended to expand the duty of the Core from the classic nucleic acid technology lab to a group of modern labs to include functional genomics. The term """"""""functional"""""""" is interpreted to keep expanding the frontier that is created by high-throughput genomic research on gene expression to move into the actual functions of proteins produced and their interactions. Reflecting the complexity of these ever-expanding cutting-edge sciences/technologies. The main objective of this service and facility core is to promote the use of modern techniques and approaches in functional genomics and molecular biology among Center investigators, their collaborators, affiliate scientists, and pilot project recipients. The Core functions to provide access, training, and assistance to students, postdoctoral fellows, and staff members with regards to specific molecular techniques and instrumentation, to offer expert advice in experimental design and approaches using these technologies, to assist in data analysis and interpretation and method troubleshooting, to suggest appropriate reference materials and information relative to specific techniques and methodological approaches, to act as a general resource to assist in the integration of molecular biology into existing programs and projects, and to facilitate the education of Center researchers in molecular biological approaches and techniques. Accordingly, the teaching and training of graduate students and staff is an integral part of the operation.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES005707-11
Application #
6588131
Study Section
Project Start
2002-04-22
Project End
2007-03-31
Budget Start
Budget End
Support Year
11
Fiscal Year
2002
Total Cost
$73,467
Indirect Cost
Name
University of California Davis
Department
Type
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Sirish, Padmini; Li, Ning; Timofeyev, Valeriy et al. (2016) Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol 9:
Gold, Ellen B; Blount, Benjamin C; O'Neill Rasor, Marianne et al. (2013) Thyroid hormones and thyroid disease in relation to perchlorate dose and residence near a superfund site. J Expo Sci Environ Epidemiol 23:399-408
Xiao, Hong; McCurdy, Stephen A; Stoecklin-Marois, Maria T et al. (2013) Agricultural work and chronic musculoskeletal pain among Latino farm workers: the MICASA study. Am J Ind Med 56:216-25
Moran, Francisco M; Chen, Jiangang; Gee, Nancy A et al. (2013) Dehydroepiandrosterone sulfate levels reflect endogenous luteinizing hormone production and response to human chorionic gonadotropin challenge in older female macaque (Macaca fascicularis). Menopause 20:329-35
Kim, In-Hae; Nishi, Kosuke; Kasagami, Takeo et al. (2012) Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase. Bioorg Med Chem Lett 22:5889-92
Plopper, C G; Joad, J P; Miller, L A et al. (2012) Lung effects of inhaled corticosteroids in a rhesus monkey model of childhood asthma. Clin Exp Allergy 42:1104-18
Tsuji, Mayumi; Kawamoto, Toshihiro; Koriyama, Chihaya et al. (2012) IL-22 mRNA expression in blood samples as a useful biomarker for assessing the adverse health effects of PCBs on allergic children. Int J Environ Res Public Health 9:4321-32
Chan, Jackie K W; Fanucchi, Michelle V; Anderson, Donald S et al. (2011) Susceptibility to inhaled flame-generated ultrafine soot in neonatal and adult rat lungs. Toxicol Sci 124:472-86
Tabares-da Rosa, Sofia; Rossotti, Martin; Carleiza, Carmen et al. (2011) Competitive selection from single domain antibody libraries allows isolation of high-affinity antihapten antibodies that are not favored in the llama immune response. Anal Chem 83:7213-20
Sciullo, Eric M; Vogel, Christoph F; Wu, Dalei et al. (2010) Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p'-DDT in U937 macrophages. Arch Toxicol 84:957-66

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