Abstract

The CRC is led by Dr. Anna Wu. The CRC membership is multidisciplinary and is reflective of the expertise needed to study the relationship between cancer and the environment (Table 1.4). Members have expertise in epidemiology, cancer biology, statistical genetics and bioinformatics, among other disciplines. This research core works closely with the BFC and with the IHSFC (GIS, molecular biology, and study implementation). It shares common methodological challenges with the CERC including study design, exposure assessment, and analytic methods as well as insights on common biological mechanisms and pathways underlying the pathogenesis of CVD/respiratory diseases and carcinogenesis. The CRC also contributes to several ongoing initiatives including the Sunlight in Health and Disease initiative. Members of the CRC meet regularly for planning research and initiative activities, CDP activities, workshops and retreat topics, and outreach activities. The CRC actively interacts with a related center. The USC Center for Transdisciplinary Research on Energetics and Cancer (TREC) that has a major focus on the contribution of the built environment on obesity and cancer.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES007048-19
Application #
8650870
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
19
Fiscal Year
2014
Total Cost
$20,789
Indirect Cost
$7,956

  Institution

Name
University of Southern California
Department
Type
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089

  Publications

Moss, Lilit C; Gauderman, William J; Lewinger, Juan Pablo et al. (2018) Using Bayes model averaging to leverage both gene main effects and G?×? E interactions to identify genomic regions in genome-wide association studies. Genet Epidemiol :
Chen, Wansu; Qian, Lei; Shi, Jiaxiao et al. (2018) Comparing performance between log-binomial and robust Poisson regression models for estimating risk ratios under model misspecification. BMC Med Res Methodol 18:63
Pomatto, Laura C D; Cline, Mayme; Woodward, Nicholas et al. (2018) Aging attenuates redox adaptive homeostasis and proteostasis in female mice exposed to traffic-derived nanoparticles ('vehicular smog'). Free Radic Biol Med 121:86-97
Lovett, Christopher; Cacciottolo, Mafalda; Shirmohammadi, Farimah et al. (2018) Diurnal variation in the proinflammatory activity of urban fine particulate matter (PM 2.5) by in vitro assays. F1000Res 7:596
Reiner, Anne S; Sisti, Julia; John, Esther M et al. (2018) Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women: An Update From the Women's Environmental Cancer and Radiation Epidemiology Study. J Clin Oncol 36:1513-1520
Alderete, Tanya L; Chen, Zhanghua; Toledo-Corral, Claudia M et al. (2018) Ambient and Traffic-Related Air Pollution Exposures as Novel Risk Factors for Metabolic Dysfunction and Type 2 Diabetes. Curr Epidemiol Rep 5:79-91
Laville, Vincent; Bentley, Amy R; Privé, Florian et al. (2018) VarExp: estimating variance explained by genome-wide GxE summary statistics. Bioinformatics 34:3412-3414
Kalkbrenner, Amy E; Windham, Gayle C; Zheng, Cheng et al. (2018) Air Toxics in Relation to Autism Diagnosis, Phenotype, and Severity in a U.S. Family-Based Study. Environ Health Perspect 126:037004
Stram, Douglas A; Jiang, Xuejuan; Varma, Rohit et al. (2018) Factors Associated with Prevalent Diabetic Retinopathy in Chinese Americans: The Chinese American Eye Study. Ophthalmol Retina 2:96-105
Dong, Jing; Levine, David M; Buas, Matthew F et al. (2018) Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus. Clin Gastroenterol Hepatol 16:1598-1606.e4

Showing the most recent 10 out of 653 publications