The purpose of this Research Core is to foster collaboration and sharing of data and methods among the members of the group in a manner which will enhance existing Center projects and motivate proposals for future studies.
The specific aims of the Toxicokinetic Susceptibility Research Core are to: 1) support and expand collaborative research in toxicokinetic and toxicodynamic susceptibility that builds on both stochastic and mechanistic traditions; 2) establish effective mechanisms for sharing ideals, discussing research in progress, and fostering new interdisciplinary ventures through regular Core meetings; 3) promote innovative research that incorporates population approaches into biomarker studies; and, 4) foster state-of-the-art biomarker measurements into research projects of other Center investigators, particularly field epidemiologists.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES010126-02
Application #
6575687
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
2002-04-01
Project End
2003-03-31
Budget Start
Budget End
Support Year
2
Fiscal Year
2002
Total Cost
$73,467
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
van Bömmel, Alena; Love, Michael I; Chung, Ho-Ryun et al. (2018) coTRaCTE predicts co-occurring transcription factors within cell-type specific enhancers. PLoS Comput Biol 14:e1006372
McNeill, Robert S; Stroobant, Emily E; Smithberger, Erin et al. (2018) PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition. PLoS One 13:e0200014
Daniels, Julie L (2018) Considerations for Studying Folate Beyond the Typical Range of Exposure. Paediatr Perinat Epidemiol 32:112-113
Reidel, Boris; Radicioni, Giorgia; Clapp, Phillip W et al. (2018) E-Cigarette Use Causes a Unique Innate Immune Response in the Lung, Involving Increased Neutrophilic Activation and Altered Mucin Secretion. Am J Respir Crit Care Med 197:492-501
Tennyson, Robert L; Gettler, Lee T; Kuzawa, Christopher W et al. (2018) Lifetime socioeconomic status and early life microbial environments predict adult blood telomere length in the Philippines. Am J Hum Biol 30:e23145
Thomas, Nancy E; Edmiston, Sharon N; Orlow, Irene et al. (2018) Inherited Genetic Variants Associated with Melanoma BRAF/NRAS Subtypes. J Invest Dermatol 138:2398-2404
Porrello, Alessandro; Leslie, Patrick L; Harrison, Emily B et al. (2018) Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking. Nat Commun 9:1988
Manuck, Tracy A; Smeester, Lisa; Martin, Elizabeth M et al. (2018) Epigenetic Regulation of the Nitric Oxide Pathway, 17-? Hydroxyprogesterone Caproate, and Recurrent Preterm Birth. Am J Perinatol 35:721-728
Barrington, William T; Wulfridge, Phillip; Wells, Ann E et al. (2018) Improving Metabolic Health Through Precision Dietetics in Mice. Genetics 208:399-417
Cui, Tianqu; Zeng, Zhexi; Dos Santos, Erickson O et al. (2018) Development of a hydrophilic interaction liquid chromatography (HILIC) method for the chemical characterization of water-soluble isoprene epoxydiol (IEPOX)-derived secondary organic aerosol. Environ Sci Process Impacts 20:1524-1536

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