Abstract

The goal of the Biomarker Facility Core is to provide access to state of the art facilities for mass spectrometry, microarray, proteomics, metabolomics, mouse genotyping, DNA damage and immunohistochemistry for members of the CEHS to facilitate and enhance research on environmentally related disease. This will be accomplished by the following objectives: 1) to make available to Center members well equipped laboratories for analytical, molecular, genomic and histochemical biomarkers; 2) to assist Center members with experimental design, tissue collection and assays of various biomarkers; 3) to foster the application of biomarkers in pilot projects and new collaborative research projects; 4) to provide education and training in methods related to biomarkers.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES010126-06
Application #
7311975
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2006-04-01
Budget End
2007-03-31
Support Year
6
Fiscal Year
2006
Total Cost
$303,122
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Marks, Daniel L; Blackmon, Richard L; Oldenburg, Amy L (2018) Diffusion tensor optical coherence tomography. Phys Med Biol 63:025007
Sarnowski, Chloé; Kavousi, Maryam; Isaacs, Steve et al. (2018) Genetic variants associated with earlier age at menopause increase the risk of cardiovascular events in women. Menopause 25:451-457
Kelley, Dannielle E; Boynton, Marcella H; Noar, Seth M et al. (2018) Effective Message Elements for Disclosures About Chemicals in Cigarette Smoke. Nicotine Tob Res 20:1047-1054
Doherty, Brett T; Hoffman, Kate; Keil, Alexander P et al. (2018) Prenatal exposure to organophosphate esters and cognitive development in young children in the Pregnancy, Infection, and Nutrition Study. Environ Res 169:33-40
Wang, Ting; Wang, Xiaofei; Zhou, Haibo et al. (2018) Auxiliary variable-enriched biomarker-stratified design. Stat Med 37:4610-4635
Isom, Daniel G; Page, Stephani C; Collins, Leonard B et al. (2018) Coordinated regulation of intracellular pH by two glucose-sensing pathways in yeast. J Biol Chem 293:2318-2329
Taylor, Kyla W; Troester, Melissa A; Herring, Amy H et al. (2018) Associations between Personal Care Product Use Patterns and Breast Cancer Risk among White and Black Women in the Sister Study. Environ Health Perspect 126:027011
Pan, Yinghao; Cai, Jianwen; Longnecker, Matthew P et al. (2018) Secondary outcome analysis for data from an outcome-dependent sampling design. Stat Med 37:2321-2337
Ryan, Calen P; Hayes, M Geoffrey; Lee, Nanette R et al. (2018) Reproduction predicts shorter telomeres and epigenetic age acceleration among young adult women. Sci Rep 8:11100
Chiong, Charlotte M; Reyes-Quintos, Ma Rina T; Yarza, Talitha Karisse L et al. (2018) The SLC26A4 c.706C>G (p.Leu236Val) Variant is a Frequent Cause of Hearing Impairment in Filipino Cochlear Implantees. Otol Neurotol 39:e726-e730

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