Abstract

The goal of the Biomarker Facility Core is to provide access to state of the art facilities for mass spectrometry, microarray, proteomics, metabolomics, mouse genotyping, DNA damage and immunohistochemistry for members of the CEHS to facilitate and enhance research on environmentally related disease. This will be accomplished by the following objectives: 1) to make available to Center members well equipped laboratories for analytical, molecular, genomic and histochemical biomarkers; 2) to assist Center members with experimental design, tissue collection and assays of various biomarkers; 3) to foster the application of biomarkers in pilot projects and new collaborative research projects; 4) to provide education and training in methods related to biomarkers.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES010126-08
Application #
7596362
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
8
Fiscal Year
2008
Total Cost
$406,071
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Little, Michael S; Pellock, Samuel J; Walton, William G et al. (2018) Structural basis for the regulation of ?-glucuronidase expression by human gut Enterobacteriaceae. Proc Natl Acad Sci U S A 115:E152-E161
Hoffman, Kate; Stapleton, Heather M; Lorenzo, Amelia et al. (2018) Prenatal exposure to organophosphates and associations with birthweight and gestational length. Environ Int 116:248-254
Bhatt, Aadra P; Gunasekara, Dulan B; Speer, Jennifer et al. (2018) Nonsteroidal Anti-Inflammatory Drug-Induced Leaky Gut Modeled Using Polarized Monolayers of Primary Human Intestinal Epithelial Cells. ACS Infect Dis 4:46-52
Anderson, Chelsea; Milne, Ginger L; Park, Yong-Moon Mark et al. (2018) Cardiovascular disease risk factors and oxidative stress among premenopausal women. Free Radic Biol Med 115:246-251
Butler, Eboneé N; Bensen, Jeannette T; Chen, Mengjie et al. (2018) Prediagnostic Smoking Is Associated with Binary and Quantitative Measures of ER Protein and ESR1 mRNA Expression in Breast Tumors. Cancer Epidemiol Biomarkers Prev 27:67-74
Laudermilk, Lucas T; Thomas, Joseph M; Kelada, Samir N (2018) Differential Regulation of Zfp30 Expression in Murine Airway Epithelia Through Altered Binding of ZFP148 to rs51434084. G3 (Bethesda) 8:687-693
Ballantine, Jami L; Carlson, Jenna C; Ferreira Zandoná, Andrea G et al. (2018) Exploring the genomic basis of early childhood caries: a pilot study. Int J Paediatr Dent 28:217-225
Bauer, Anna E; Avery, Christy L; Shi, Min et al. (2018) A Family Based Study of Carbon Monoxide and Nitric Oxide Signalling Genes and Preeclampsia. Paediatr Perinat Epidemiol 32:1-12
Marrus, Natasha; Eggebrecht, Adam T; Todorov, Alexandre et al. (2018) Walking, Gross Motor Development, and Brain Functional Connectivity in Infants and Toddlers. Cereb Cortex 28:750-763
Burbank, Allison J; Duran, Charity G; Pan, Yinghao et al. (2018) Gamma tocopherol-enriched supplement reduces sputum eosinophilia and endotoxin-induced sputum neutrophilia in volunteers with asthma. J Allergy Clin Immunol 141:1231-1238.e1

Showing the most recent 10 out of 1900 publications