The Pilot Project Program is a key component of the Center of Excellence in Environmental Toxicology (CEET), The Pilot Project Program is aimed at funding new directions in environmental health research. These grants represent one vehicle by which the Center can continue to enrich, attract and support innovative research that may not be ready for direct NIH-funding, In addition, Pilot Projects can be used to fund collaborative research that may become a component of a multi-investigator award, the development of technologies that may benefit other CEET investigators, and to take the CEET into new directions. The Pilot Project Program serves to attract junior investigators and established faculty new to environmental health sciences to the CEET. The Program encourages applications that address community-based needs and can be proposed by COEC members. The Pilot Project Program also encourages applications that will seed patient and human population-based research that may require the resources of the Integrative Health Sciences Facility Core (IHSFC). This Program represents an important vehicle by which the Center can rejuvenate its membership and draw natural alliances with new faculty. The goals of the Pilot Project Program are to: ? Support career development of junior faculty in environmental health science ? Attract established investigators into environmental health science ? Develop technologies that may benefit other CEET investigators ? Fund collaborative research that may lead to multi-investigator grant applications ? Stimulate translational research themes in environmental health science ? Fund community based research projects identified by COEC members ? Fund patient and population based exposure research that will utilize the IHSFC The CEET is in its third year of funding and has awarded 14 Pilot Projects. Four of these awards were funded January 01, 2009. Of the ten Pilot Projects that have had sufficient time to provide a return on the investment, $4,085,050 in direct costs have been generated for an investment of $225,000 which is greater than 18:1. This value is deflated to 13.1: 1 if the newly funded Pilot Projects are counted. Pilot Project funding has led to 12 articles published in the scientific literature.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES013508-06
Application #
8248249
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
2011-04-01
Project End
2015-03-31
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
6
Fiscal Year
2011
Total Cost
$151,448
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Friedman, Elliot S; Bittinger, Kyle; Esipova, Tatiana V et al. (2018) Microbes vs. chemistry in the origin of the anaerobic gut lumen. Proc Natl Acad Sci U S A 115:4170-4175
Sullivan, John; Croisant, Sharon; Howarth, Marilyn et al. (2018) Implications of the GC-HARMS Fishermen's Citizen Science Network: Issues Raised, Lessons Learned, and Next Steps for the Network and Citizen Science. New Solut :1048291118810871
Shastri, Nishita; Tsai, Yu-Chen; Hile, Suzanne et al. (2018) Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition. Mol Cell 72:222-238.e11
Pietrofesa, Ralph A; Chatterjee, Shampa; Park, Kyewon et al. (2018) Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605) Reduces Asbestos-Induced Cytotoxicity in an Nrf2-Dependent and -Independent Manner. Antioxidants (Basel) 7:
Scherpereel, Arnaud; Wallyn, Frederic; Albelda, Steven M et al. (2018) Novel therapies for malignant pleural mesothelioma. Lancet Oncol 19:e161-e172
Bansal, A; Li, C; Xin, F et al. (2018) Transgenerational effects of maternal bisphenol: a exposure on offspring metabolic health. J Dev Orig Health Dis :1-12
Rashid, Cetewayo S; Bansal, Amita; Simmons, Rebecca A (2018) Oxidative Stress, Intrauterine Growth Restriction, and Developmental Programming of Type 2 Diabetes. Physiology (Bethesda) 33:348-359
Kress, Geraldine J; Liao, Fan; Dimitry, Julie et al. (2018) Regulation of amyloid-? dynamics and pathology by the circadian clock. J Exp Med 215:1059-1068
Wang, Jessica; Um, Phoebe; Dickerman, Barbra A et al. (2018) Zinc, Magnesium, Selenium and Depression: A Review of the Evidence, Potential Mechanisms and Implications. Nutrients 10:
Sanders, Alison P; Svensson, Katherine; Gennings, Chris et al. (2018) Prenatal lead exposure modifies the effect of shorter gestation on increased blood pressure in children. Environ Int 120:464-471

Showing the most recent 10 out of 835 publications