-PILOT PROJECT PROGRAM The CHHE Pilot Project Program (PPP) will advance environmental health research by fostering collaborations, increasing multidisciplinary research, and aiding the career development of early career investigators. The overarching goal of CHHE?s PPP is to support research aimed at understanding the adverse impacts of environmental factors on human health and disease. The CHHE PPP aims to enhance the impact of environmental health sciences (EHS) research and increase the environmental health sciences identity at NC State University, East Carolina University (ECU) Brody School of Medicine, and North Carolina Central University (NCCU). Pilot project funding is awarded ($25,000/project) to collect preliminary data that: 1) advances the mission of CHHE and the National Institute of Environmental Health Sciences (NIEHS) Strategic Plan and 2) supports applications for external funding from the NIEHS, other NIH Institutes, and other Federal agencies. The PPP supports high quality basic, applied, clinical and public health research, especially in areas relevant to the four CHHE research interest groups which are: 1) Emerging Contaminants, 2) Environmental Genetics and Epigenetics, 3) Pulmonary Health, and 4) Behavior and Neuroscience. CHHE PPP also supports high quality environmental health research outside of its thematic areas, as well as high risk/high gain research that addresses environmental health concerns and encourages the use of CHHE?s Facility Cores and resources. The CHHE PPP accepts applications from CHHE members, as well as non-member faculty from NC State University, ECU, and NCCU. This PPP policy functions to attract/recruit new members, bring new skill sets to the Center, link researchers and community partners to address environmental health questions, and increase the Center?s multidisciplinary research base. In this competing renewal, the PPP is adding a new program that supports community-engaged projects. CHHE will direct $300,000/year ($200,000 NIEHS and $100,000 NC State) to its PPP and expects to fund 12 pilot projects/year at $25,000/project. CHHE PPP will sponsor at least 1 pilot project/year for community-engaged projects.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES025128-06
Application #
9911377
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
6
Fiscal Year
2020
Total Cost
Indirect Cost
Name
North Carolina State University Raleigh
Department
Type
DUNS #
042092122
City
Raleigh
State
NC
Country
United States
Zip Code
27695
House, John S; Mendez, Michelle; Maguire, Rachel L et al. (2018) Periconceptional Maternal Mediterranean Diet Is Associated With Favorable Offspring Behaviors and Altered CpG Methylation of Imprinted Genes. Front Cell Dev Biol 6:107
Gonzalez-Nahm, Sarah; Mendez, Michelle A; Benjamin-Neelon, Sara E et al. (2018) DNA methylation of imprinted genes at birth is associated with child weight status at birth, 1 year, and 3 years. Clin Epigenetics 10:90
Cao, Jinyan; Willett, Jaime A; Dorris, David M et al. (2018) Sex Differences in Medium Spiny Neuron Excitability and Glutamatergic Synaptic Input: Heterogeneity Across Striatal Regions and Evidence for Estradiol-Dependent Sexual Differentiation. Front Endocrinol (Lausanne) 9:173
Israel, Jennifer W; Chappell, Grace A; Simon, Jeremy M et al. (2018) Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription. Mamm Genome 29:153-167
Arambula, Sheryl E; Jima, Dereje; Patisaul, Heather B (2018) Prenatal bisphenol A (BPA) exposure alters the transcriptome of the neonate rat amygdala in a sex-specific manner: a CLARITY-BPA consortium study. Neurotoxicology 65:207-220
Chiu, Weihsueh A; Guyton, Kathryn Z; Martin, Matthew T et al. (2018) Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups. ALTEX 35:51-64
Prins, Gail S; Patisaul, Heather B; Belcher, Scott M et al. (2018) CLARITY-BPA academic laboratory studies identify consistent low-dose Bisphenol A effects on multiple organ systems. Basic Clin Pharmacol Toxicol :
Cao, Jinyan; Dorris, David M; Meitzen, John (2018) Electrophysiological properties of medium spiny neurons in the nucleus accumbens core of prepubertal male and female Drd1a-tdTomato line 6 BAC transgenic mice. J Neurophysiol 120:1712-1727
Duke, Katherine S; Taylor, Alexia J; Ihrie, Mark D et al. (2018) Signal Transducer and Activator of Transcription 1 Regulates Multiwalled Carbon Nanotube-induced Pulmonary Fibrosis in Mice via Suppression of Transforming Growth Factor-?1 Production and Signaling. Ann Am Thorac Soc 15:S129-S130
Gomih, Ayodele; Smith, Jennifer S; North, Kari E et al. (2018) DNA methylation of imprinted gene control regions in the regression of low-grade cervical lesions. Int J Cancer 143:552-560

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