We are continuing a research program in the physiology, psychophysics and biophysical analysis of normal and abnormal visual and oculomotor processes. productive collaboration between basic scientists and clinical investigators will be emphasized. The program will comprise work in the following major subdivision: 1) Human ocular motility - quantatitive study of the mechanisms underlying the control and mechanics of normal and abnormal eye movements applied to the calculation of strabismus surgery. 2) Clinical alteration of extraocular muscle function - an alternative to strabismus surgery. 3) Human eyelid movements and forces - evaluated for their feasibility in diagnosis and guidance of ptosis surgery. 4) Three-dimensional aspects of vision and oculomotility - a project to assess translational and rotational movements in an accurate quantitative fashion. 5) A temporal aspect of binocular vision -testing temporal resolution and contour orientation threshold at the fovea. 6) Etiology and diagnosis of retinal and cortical diseases - electrophysiological studies of local cortical properties and binocular interactions in amblyopia, and psychophysical studies in glaucoma. 7) Studies of the oculomoter system of alert primates - single neuron studies of plastic adaptation of the visual-vestibular system. 8) Experimental studies of adenoviral ocular infections - developing immunoenzyme diagnostic tests for adenovirus keratoconjunctivitis. 9) Tactile mobility aid evaluation - studying the feasibility of a system providing the blind with greater spatial resolution and localization capability.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY001186-13
Application #
3102406
Study Section
Vision Research and Training Committee (VSN)
Project Start
1976-06-01
Project End
1986-06-30
Budget Start
1985-07-01
Budget End
1986-06-30
Support Year
13
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Medical Research Institute of San Fran
Department
Type
DUNS #
City
San Francisco
State
CA
Country
United States
Zip Code
94115
McKee, S P; Bravo, M J; Smallman, H S et al. (1995) The 'uniqueness constraint' and binocular masking. Perception 24:49-65
Harrad, R A; McKee, S P; Blake, R et al. (1994) Binocular rivalry disrupts stereopsis. Perception 23:15-28
McKee, S P; Bravo, M J; Taylor, D G et al. (1994) Stereo matching precedes dichoptic masking. Vision Res 34:1047-60
McKee, S P; Harrad, R A (1993) Fusional suppression in normal and stereoanomalous observers. Vision Res 33:1645-58
McKee, S P; Welch, L (1992) The precision of size constancy. Vision Res 32:1447-60
McKee, S P; Welch, L; Taylor, D G et al. (1990) Finding the common bond: stereoacuity and the other hyperacuities. Vision Res 30:879-91
McKee, S P; Welch, L (1989) Is there a constancy for velocity? Vision Res 29:553-61
Nakayama, K; Silverman, G H (1988) The aperture problem--I. Perception of nonrigidity and motion direction in translating sinusoidal lines. Vision Res 28:739-46
Nakayama, K; Silverman, G H (1988) The aperture problem--II. Spatial integration of velocity information along contours. Vision Res 28:747-53
McKee, S P; Levi, D M (1987) Dichoptic hyperacuity: the precision of nonius alignment. J Opt Soc Am A 4:1104-8

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