Abstract

The Wilmer Core Grant has productively supported over thirty National Eye Institute-funded principal investigators with the following four modules: 1. Electron Microscopy 2. Computer 3. Biostatistics/Clinical Vision Research Center 4. Machine Shop We plan continuation of these four service areas, with the addition of a fifth module: 5. Molecular Biology and Genetics Each of the Core units will provide important research enhancement to a moderate or maximum usage level for at least eight National Eye Institute funded researchers, with facilitation of collaborative studies. We will encourage some sharing of Core Grant resources and services with non-NEI funded collaborators and with investigators new to vision research, as time permits.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY001765-23
Application #
2710803
Study Section
Special Emphasis Panel (SRC (04))
Project Start
1979-07-01
Project End
1999-06-30
Budget Start
1998-07-01
Budget End
1999-06-30
Support Year
23
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Wilson, David R; Sen, Rupashree; Sunshine, Joel C et al. (2018) Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy. Nanomedicine 14:237-246
Fernandes, Kimberly A; Mitchell, Katherine L; Patel, Amit et al. (2018) Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury. Exp Eye Res 171:54-61
Date, Abhijit A; Halpert, Gilad; Babu, Taarika et al. (2018) Mucus-penetrating budesonide nanosuspension enema for local treatment of inflammatory bowel disease. Biomaterials 185:97-105
Meyer, Randall A; Mathew, Mohit P; Ben-Akiva, Elana et al. (2018) Anisotropic biodegradable lipid coated particles for spatially dynamic protein presentation. Acta Biomater 72:228-238
Goldberg, Morton F; McLeod, Scott; Tso, Mark et al. (2018) Ocular Histopathology and Immunohistochemical Analysis in the Oldest Known Individual with Autosomal Dominant Vitreoretinochoroidopathy. Ophthalmol Retina 2:360-378
Park, Tea Soon; Zimmerlin, Ludovic; Evans-Moses, Rebecca et al. (2018) Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency. J Vis Exp :
Hinkle, Jared T; Perepezko, Kate; Bakker, Catherine C et al. (2018) Domain-specific cognitive impairment in non-demented Parkinson's disease psychosis. Int J Geriatr Psychiatry 33:e131-e139
Duncan, Gregg A; Kim, Namho; Colon-Cortes, Yanerys et al. (2018) An Adeno-Associated Viral Vector Capable of Penetrating the Mucus Barrier to Inhaled Gene Therapy. Mol Ther Methods Clin Dev 9:296-304
Long, Da; Kanan, Yogita; Shen, Jikui et al. (2018) VEGF/VEGFR2 blockade does not cause retinal atrophy in AMD-relevant models. JCI Insight 3:
Liu, Melissa M; Cho, Chris; Jefferys, Joan L et al. (2018) Use of Optical Coherence Tomography by Nonexpert Personnel as a Screening Approach for Glaucoma. J Glaucoma 27:64-70

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