ANIMAL SERVICES CORE The Animal Services Core is structured to meet the evolving needs of investigators for translational research by providing resources to develop experimental animal models of ocular diseases and test the delivery and efficacy of new therapeutic agents. The goals are: 1) to provide expert assistance and oversight in the management of transgenic and gene knockout/knockin animal colonies, including their genotyping; 2) to make available the use of animal facilities and equipment, provide guidance in their utilization, and supervise the performance of animal procedures and tissue harvesting; 3) to make available equipment for development and generation of animal models of ocular diseases and pathologic eye conditions; 4) to provide assistance in imaging of live animals; 5) to serve as a liaison between investigators and the University's animal facilities and services.

Public Health Relevance

ANIMAL SERVICES CORE The Animal Services Core provides shared equipment and technical staff to develop experimental animal models and test new regenerative therapies in translational vision science research.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY001792-40
Application #
9772472
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2019-09-30
Budget End
2020-09-29
Support Year
40
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Type
DUNS #
098987217
City
Chicago
State
IL
Country
United States
Zip Code
60612
Roth, Steven; Dreixler, John; Newman, Nancy J (2018) Haemodilution and head-down tilting induce functional injury in the rat optic nerve: A model for peri-operative ischemic optic neuropathy. Eur J Anaesthesiol 35:840-847
Blair, Norman P; Tan, Michael R; Felder, Anthony E et al. (2018) Retinal tissue oxygen tension and consumption during light flicker stimulation in rat. Exp Eye Res 175:207-211
Son, Taeyoon; Alam, Minhaj; Toslak, Devrim et al. (2018) Functional optical coherence tomography of neurovascular coupling interactions in the retina. J Biophotonics 11:e201800089
Gao, X Raymond; Huang, Hua; Nannini, Drew R et al. (2018) Genome-wide association analyses identify new loci influencing intraocular pressure. Hum Mol Genet 27:2205-2213
Alam, Minhaj; Son, Taeyoon; Toslak, Devrim et al. (2018) Combining ODR and Blood Vessel Tracking for Artery-Vein Classification and Analysis in Color Fundus Images. Transl Vis Sci Technol 7:23
Francis, Andrew W; Wanek, Justin; Shahidi, Mahnaz (2018) Assessment of Global and Local Alterations in Retinal Layer Thickness in Ins2 (Akita) Diabetic Mice by Spectral Domain Optical Coherence Tomography. J Ophthalmol 2018:7253498
Toslak, Devrim; Ayata, Ali; Liu, Changgeng et al. (2018) WIDE-FIELD SMARTPHONE FUNDUS VIDEO CAMERA BASED ON MINIATURIZED INDIRECT OPHTHALMOSCOPY. Retina 38:438-441
Shahidi, Mahnaz; Felder, Anthony E; Tan, Ou et al. (2018) Retinal Oxygen Delivery and Metabolism in Healthy and Sickle Cell Retinopathy Subjects. Invest Ophthalmol Vis Sci 59:1905-1909
Cao, Dingcai; Chang, Adam; Gai, Shaoyan (2018) Evidence for an impact of melanopsin activation on unique white perception. J Opt Soc Am A Opt Image Sci Vis 35:B287-B291
Moss, Heather E; Vangipuram, Gautam; Shirazi, Zainab et al. (2018) Retinal Vessel Diameters Change Within 1 Hour of Intracranial Pressure Lowering. Transl Vis Sci Technol 7:6

Showing the most recent 10 out of 1181 publications