Abstract

Continuing support is requestd for Core Center facilities and services to strengthen and promote collaborative interactions between the sixteen vision researchers that comprise the Core faculty at the Cullen Eye Institute of Baylor College of Medicine. The major programmatic areas include diseases of the retina and choroid, the cornea and the sensory motor visual system. Research activities include investigation of the anatomy, biochemistry, physiology and pathology of the neural retina, retinal pigment epithelium and choroid, retinal organization and information processing, the role of herpes virus in corneal disease, endogenous fungal endophthalmitis and visual dysfunction of strabismus and amblyopia.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY002520-08
Application #
3102524
Study Section
Vision Research and Training Committee (VSN)
Project Start
1979-07-01
Project End
1989-06-30
Budget Start
1986-07-01
Budget End
1987-06-30
Support Year
8
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
Baylor College of Medicine
Department
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Wang, Hongxia; Dewell, Richard B; Zhu, Ying et al. (2018) Feedforward Inhibition Conveys Time-Varying Stimulus Information in a Collision Detection Circuit. Curr Biol 28:1509-1521.e3
Zhu, Ying; Dewell, Richard B; Wang, Hongxia et al. (2018) Pre-synaptic Muscarinic Excitation Enhances the Discrimination of Looming Stimuli in a Collision-Detection Neuron. Cell Rep 23:2365-2378
Dewell, Richard Burkett; Gabbiani, Fabrizio (2018) Biophysics of object segmentation in a collision-detecting neuron. Elife 7:
Ko, Byung Yi; Xiao, Yangyan; Barbosa, Flavia L et al. (2018) Goblet cell loss abrogates ocular surface immune tolerance. JCI Insight 3:
Shen, Guofu; Link, Schuyler; Kumar, Sandeep et al. (2018) Characterization of Retinal Ganglion Cell and Optic Nerve Phenotypes Caused by Sustained Intracranial Pressure Elevation in Mice. Sci Rep 8:2856
Eblimit, Aiden; Agrawal, Smriti Akshay; Thomas, Kandace et al. (2018) Conditional loss of Spata7 in photoreceptors causes progressive retinal degeneration in mice. Exp Eye Res 166:120-130
Denfield, George H; Ecker, Alexander S; Shinn, Tori J et al. (2018) Attentional fluctuations induce shared variability in macaque primary visual cortex. Nat Commun 9:2654
Wang, Changjun; Zaheer, Mahira; Bian, Fang et al. (2018) Sjögren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice. Int J Mol Sci 19:
Kumar, Sandeep; Lambert, Alyssia; Rainier, Jon et al. (2018) Disruption of Rhodopsin Dimerization in Mouse Rod Photoreceptors by Synthetic Peptides Targeting Dimer Interface. Methods Mol Biol 1753:115-128
Zaneveld, Smriti Agrawal; Eblimit, Aiden; Liang, Qingnan et al. (2018) Gene Therapy Rescues Retinal Degeneration in Receptor Expression-Enhancing Protein 6 Mutant Mice. Hum Gene Ther :

Showing the most recent 10 out of 349 publications