Five years of renewed support are requested for three core facilities in the Department of Brain and Cognitive Sciences at the Massachusetts Institute of Technology. Ours is a growing department which at present has 14 investigators who carry out research on vision, the visual system and the oculomotor system. We are in the process of making additional appointments in these areas. We have 10 grants from the National Eye Institute. The research carried out by the 14 investigators of the Core Group includes the following areas of research: (1) neurophysiological studies of the visual and oculomotor systems, (2) anatomical studies of the visual and oculomotor systems, (3) developmental studies of the vision and visuomotor function, (4) psychophysical studies of visual functions in non-human primates, (5) psychophysical studies of visual functions in normal human and patient populations, (6) computational analyses of vision and eye movement and (7) molecular and genetic studies of visual system formation. The three facilities supported by the Core Grant, the Instrument Shop, the Electronics Shop and the Biostatistical Module are in extensive use by the Core Group. During the past four years these investigators have been most productive and have published more than 200 papers. The Core Facilities have made a highly significant contribution to the overall research efforts of this group and have fostered interaction among investigators involved in vision and visuomotor research. Continued support of the Core Facilities will be of great benefit to our future investigations.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY002621-20
Application #
2459054
Study Section
Special Emphasis Panel (SRC (01))
Project Start
1978-08-01
Project End
1998-07-31
Budget Start
1997-08-01
Budget End
1998-07-31
Support Year
20
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Baldauf, Daniel; Desimone, Robert (2014) Neural mechanisms of object-based attention. Science 344:424-7
Li, Nuo; Dicarlo, James J (2012) Neuronal learning of invariant object representation in the ventral visual stream is not dependent on reward. J Neurosci 32:6611-20
Vercelli, Alessandro; Boido, Marina; Jhaveri, Sonal (2012) NADPH diaphorase expression in superior colliculus of developing, aging and visually deafferented rats. Ital J Anat Embryol 117:142-66
Zhou, Huihui; Desimone, Robert (2011) Feature-based attention in the frontal eye field and area V4 during visual search. Neuron 70:1205-17
Han, Xue; Qian, Xiaofeng; Bernstein, Jacob G et al. (2009) Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain. Neuron 62:191-8
Lyckman, A W; Moya, K L; Confaloni, A et al. (2000) Early postnatal expression of L1 by retinal fibers in the optic tract and synaptic targets of the Syrian hamster. J Comp Neurol 423:40-51
Ling, C; Schneider, G E; Jhaveri, S (1998) Target-specific morphology of retinal axon arbors in the adult hamster. Vis Neurosci 15:559-79
Wu, D Y; Schneider, G E; Silver, J et al. (1998) A role for tectal midline glia in the unilateral containment of retinocollicular axons. J Neurosci 18:8344-55
Ling, C; Jhaveri, S; Schneider, G E (1997) Target- as well as source-derived factors direct the morphogenesis of anomalous retino-thalamic projections. J Comp Neurol 388:454-66
Ling, C; Schneider, G E; Northmore, D et al. (1997) Afferents from the colliculus, cortex, and retina have distinct terminal morphologies in the lateral posterior thalamic nucleus. J Comp Neurol 388:467-83

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