Funds are requested to renew core support for 4 core modules. I. Tissue Culture. This laboratory provides modern facilities for the culture of a variety of ocular cells used in different research projects. Five primary and 11 secondary users base important aspects of their research on this laboratory. Core support is requested for a supervisor and basic supplies. II. Histopathology. This important laboratory provides all facilities for tissue processing for light microscopy. It is heavily utilized with 10 primary and 11 secondary users. Core support is requested for a supervisor and basic supplies. III. Ultrastructure (EM). This laboratory provides all equipment and support for scanning and transmission electron microscopy. It is used to full capacity by 5 primary and 17 secondary users. Core support is requested for a supervisor and basic supplies. IV. Vivarium. This modern facility accommodates primates, rodents, rabbits and cats and provides for sterile surgery and special procedures such as necropsy, electroretinography, echography and fundus photography. The vivarium is essential to our entire basic science research effort with 11 primary and 4 secondary users. Core support is requested for a supervisor, a senior vivarium technician and basic supplies.
| Kim, Hwa Sun; Huang, Shun-Ping; Lee, Eun-Jin et al. (2018) Identifying Key Networks Linked to Light-Independent Photoreceptor Degeneration in Visual Arrestin 1 Knockout Mice. Adv Exp Med Biol 1074:281-287 |
| Gonzalez Jr, Jose M; Ko, Minhee K; Masedunskas, Andrius et al. (2017) Toward in vivo two-photon analysis of mouse aqueous outflow structure and function. Exp Eye Res 158:161-170 |
| Carelli, Valerio; La Morgia, Chiara; Ross-Cisneros, Fred N et al. (2017) Optic neuropathies: the tip of the neurodegeneration iceberg. Hum Mol Genet 26:R139-R150 |
| Kim, Esther Lee; Tran, Jeffrey; Töteberg-Harms, Marc et al. (2017) Vision Loss and Recovery after Baerveldt Aqueous Tube Shunt Implantation. J Ophthalmol 2017:4140305 |
| Deming, Janise D; Van Craenenbroeck, Kathleen; Eom, Yun Sung et al. (2016) Characterization of Antibodies to Identify Cellular Expression of Dopamine Receptor 4. Adv Exp Med Biol 854:663-70 |
| Choudhury, Farzana; Varma, Rohit; Klein, Ronald et al. (2016) Age-Related Macular Degeneration and Quality of Life in Latinos: The Los Angeles Latino Eye Study. JAMA Ophthalmol 134:683-90 |
| Gonzalez Jr, Jose M; Ammar, Michael J; Ko, MinHee K et al. (2016) Optimizing two-photon multiple fluorophore imaging of the human trabecular meshwork. Mol Vis 22:203-12 |
| Ishikawa, Keijiro; Kannan, Ram; Hinton, David R (2016) Molecular mechanisms of subretinal fibrosis in age-related macular degeneration. Exp Eye Res 142:19-25 |
| Carelli, Valerio; d'Adamo, Pio; Valentino, Maria Lucia et al. (2016) Parsing the differences in affected with LHON: genetic versus environmental triggers of disease conversion. Brain 139:e17 |
| Gonzalez, Jose M; Ko, Minhee K; Pouw, Andrew et al. (2016) Tissue-based multiphoton analysis of actomyosin and structural responses in human trabecular meshwork. Sci Rep 6:21315 |
Showing the most recent 10 out of 968 publications
