This NEI P30 award provides ongoing and stable funding for four high quality and productive vision research service Modules: Instrument Design, Research Computer Programming, Biostatistics and Clinical Research, and Biological Imaging. These Modules are run by an exceptionally talented staff that has from 7 to 20 years of experience in our Core Center for Vision Research. The Modules provide needed research services to the present group of 23 Core Center vision scientists who come from 5 departments of the University of Houston (Chemistry, Physics, Electrical Engineering, and Clinical Sciences and Vision Sciences in Optometry). These Core vision scientists have diverse training and research interests;they collaborate effectively with one another, as well as with more than 100 other vision researchers at this University or other institutions. Together, our 23 Core Center investigators have 14 qualifying NEI-funded grants. The College of Optometry and University of Houston provide considerable additional commitments in support of vision research. During the past 5 years of P30 funding at this University, the Core Center has created a favorable vision research environment that has contributed directly to 186 published papers and culminated in the recruitment of 5 new vision investigators, 2 of whom currently have NEI funding. The Core Center also was crucial to the success of two clinicians (ODs) in obtaining new NEI funding for mentored clinician scientists. These accomplishments reflect our Core Center's previous and current aims that focus on stable funding, quality research services, collaborative and innovative basic, clinical and translational research, new vision researchers, and new projects converting into NIH and NEI support. Especially emphasized in the coming 5 years will be innovative research basic, clinical and translational research and recruitment of vision researchers to fill our current open positions, as well as other positions in the future. The Core Center for Vision Research in the College of Optometry at the University of Houston improves visual health by supporting investigators doing basic, clinical and translational research on vision and vision disorders.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY007551-23
Application #
7809490
Study Section
Special Emphasis Panel (ZEY1-VSN (04))
Program Officer
Liberman, Ellen S
Project Start
1997-03-01
Project End
2013-04-30
Budget Start
2010-05-01
Budget End
2011-04-30
Support Year
23
Fiscal Year
2010
Total Cost
$584,724
Indirect Cost
Name
University of Houston
Department
Type
Schools of Optometry/Ophthalmol
DUNS #
036837920
City
Houston
State
TX
Country
United States
Zip Code
77204
Gutierrez, Berenice A; Chavez, Miguel A; Rodarte, Alejandro I et al. (2018) Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells. J Biol Chem 293:7148-7159
Davis, Joshua T; Foster, William J (2018) Substrate Stiffness Influences the Time Dependence of CTGF Protein Expression in Müller Cells. Int Physiol J 1:1
Ostrin, Lisa A; Sajjadi, Auzita; Benoit, Julia S (2018) Objectively Measured Light Exposure During School and Summer in Children. Optom Vis Sci 95:332-342
McAllister, Faith; Harwerth, Ronald; Patel, Nimesh (2018) Assessing the True Intraocular Pressure in the Non-human Primate. Optom Vis Sci 95:113-119
Huang, Juan; Lentsch, Matthew J; Marsack, Jason D et al. (2018) Evaluating the use of a temperature sensor to monitor spectacle compliance in warm versus cold climates. Clin Exp Optom :
Jnawali, Ashutosh; Beach, Krista M; Ostrin, Lisa A (2018) In Vivo Imaging of the Retina, Choroid, and Optic Nerve Head in Guinea Pigs. Curr Eye Res 43:1006-1018
Abbott, Kaleb S; Queener, Hope M; Ostrin, Lisa A (2018) The ipRGC-Driven Pupil Response with Light Exposure, Refractive Error, and Sleep. Optom Vis Sci 95:323-331
Vantipalli, Srilatha; Li, Jiasong; Singh, Manmohan et al. (2018) Effects of Thickness on Corneal Biomechanical Properties Using Optical Coherence Elastography. Optom Vis Sci 95:299-308
Ostrin, Lisa A (2018) The ipRGC-driven pupil response with light exposure and refractive error in children. Ophthalmic Physiol Opt 38:503-515
Schulle, Krystal L; Berntsen, David A; Sinnott, Loraine T et al. (2018) Visual Acuity and Over-refraction in Myopic Children Fitted with Soft Multifocal Contact Lenses. Optom Vis Sci 95:292-298

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