The NEI P3O Center Core Grant for Vision Research at the University of Houston provides ongoing and stable funding for four high quality and productive vision research resource/service Modules: Instrument Design, Research Computer Programming, Biostatistics Support, and Biological Imaging. These Modules are directed by established vision scientists with NEI funding, and run by an exceptionally talented staff with considerable long-term experience in supporting and advancing innovative vision research at the University of Houston. The Modules provide needed research resources and services, with prioritized and equitable access, to the present group of 22 Core vision scientists who come from three departments at the University (Biomedical Engineering, Vision Sciences and Clinical Sciences in Optometry). These Core vision scientists have diverse training and research interests; they collaborate effectively with one another, as well as with more than 100 other vision researchers at this University or other institutions. Together, 11 of our Core investigators hold 10 active NEI R01 grants, with some other core investigators as Co-Is, as well as other NEI funding, NIH and nonfederal vision research funding. The College of Optometry and University of Houston provide substantial additional commitments in support of vision research. During the past five years of P30 funding at this University, the Core Grant has created a favorable vision research environment, including new instrumentation and core collaborative arrangements, that have contributed directly to 137 out of 230 published papers by Core investigators and supported the addition of eight investigators, established and new, to the Core group of vision scientists, four of whom brought or quickly secured NEI funding. The Core modules also were important to obtaining new NEI funding for a multicenter clinical trial. These accomplishments reflect the Core's previous and current aims reinforced by the oversight of the Administrative Core, that focus on advancing collaborative and innovative basic, translational and clinical research to increase knowledge and prevent or cure disease. Through these aims the Core grant provides stable funding, quality research services, new vision researchers, and new projects attracting NIH and NEI support. Especially emphasized in the coming five years will be innovative research basic, translational and clinical research and recruitment of vision researchers to fill our current open positions, as well as other positions in the future.

Public Health Relevance

The Center Core Grant for Vision Research at the University of Houston increases knowledge about the structure and function of the visual system, and improves visual health by supporting investigators in individual labs, and in collaborations across labs and disciplines, in doing basic, translational and clinical research on vision and vision disorders.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY007551-33
Application #
9968264
Study Section
Special Emphasis Panel (ZEY1)
Program Officer
Liberman, Ellen S
Project Start
1997-03-01
Project End
2023-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
33
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Houston
Department
Type
Schools of Optometry/Opht Tech
DUNS #
036837920
City
Houston
State
TX
Country
United States
Zip Code
77204
Jnawali, Ashutosh; Beach, Krista M; Ostrin, Lisa A (2018) In Vivo Imaging of the Retina, Choroid, and Optic Nerve Head in Guinea Pigs. Curr Eye Res 43:1006-1018
Abbott, Kaleb S; Queener, Hope M; Ostrin, Lisa A (2018) The ipRGC-Driven Pupil Response with Light Exposure, Refractive Error, and Sleep. Optom Vis Sci 95:323-331
Vantipalli, Srilatha; Li, Jiasong; Singh, Manmohan et al. (2018) Effects of Thickness on Corneal Biomechanical Properties Using Optical Coherence Elastography. Optom Vis Sci 95:299-308
Ostrin, Lisa A (2018) The ipRGC-driven pupil response with light exposure and refractive error in children. Ophthalmic Physiol Opt 38:503-515
Schulle, Krystal L; Berntsen, David A; Sinnott, Loraine T et al. (2018) Visual Acuity and Over-refraction in Myopic Children Fitted with Soft Multifocal Contact Lenses. Optom Vis Sci 95:292-298
Roberts, Tawna L; Stevenson, Scott B; Benoit, Julia S et al. (2018) Blur Detection, Depth of Field, and Accommodation in Emmetropic and Hyperopic Children. Optom Vis Sci 95:212-222
Rodarte, Elsa M; Ramos, Marco A; Davalos, Alfredo J et al. (2018) Munc13 proteins control regulated exocytosis in mast cells. J Biol Chem 293:345-358
Takahata, Toru; Patel, Nimesh B; Balaram, Pooja et al. (2018) Long-term histological changes in the macaque primary visual cortex and the lateral geniculate nucleus after monocular deprivation produced by early restricted retinal lesions and diffuser induced form deprivation. J Comp Neurol 526:2955-2972
Lentsch, Matthew J; Marsack, Jason D; Anderson, Heather A (2018) Objective measurement of spectacle wear with a temperature sensor data logger. Ophthalmic Physiol Opt 38:37-47
Skidmore, Kelsea V; Walker, Maria K; Marsack, Jason D et al. (2018) A measure of tear inflow in habitual scleral lens wearers with and without midday fogging. Cont Lens Anterior Eye :

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