Abstract

Fifty-two investigators from the Oregon Health &Science University are requesting renewal of National Eye Institute core funding to support four modules: Molecular genetics and statistics, Gene Expression, Proteomics, and Microscopy. Since its last core grant competing renewal 5 years ago, the department of ophthalmology has tripled its wet lab research space. The core users include 27 faculty members who are principal investigators on NEI supported grants, including 31 grants which are either R0Is or K08s, as well as 2 R21s and 1 R42. The investigators also receive additional NIH and foundation support. The Casey Eye Institute/Department of Ophthalmology has made a major commitment to research as should be apparent from this depth and from this growth. The core grant support from the NEI has been an essential component of this success. The department is committed to expanding its research program with core facilities serving as a major contributor to this projected growth.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY010572-17
Application #
8063873
Study Section
Special Emphasis Panel (ZEY1-VSN (03))
Program Officer
Liberman, Ellen S
Project Start
1997-05-01
Project End
2015-04-30
Budget Start
2011-05-01
Budget End
2012-04-30
Support Year
17
Fiscal Year
2011
Total Cost
$738,469
Indirect Cost

  Institution

Name
Oregon Health and Science University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239

  Publications

Loh, Allison R; Edmunds, Beth; Peter Campbell, J et al. (2018) Ophthalmic imaging in children: current practice patterns and perceived barriers. J AAPOS 22:223-225.e3
Hagag, Ahmed M; Pechauer, Alex D; Liu, Liang et al. (2018) OCT Angiography Changes in the 3 Parafoveal Retinal Plexuses in Response to Hyperoxia. Ophthalmol Retina 2:329-336
Lu, Yansha; Simonett, Joseph M; Wang, Jie et al. (2018) Evaluation of Automatically Quantified Foveal Avascular Zone Metrics for Diagnosis of Diabetic Retinopathy Using Optical Coherence Tomography Angiography. Invest Ophthalmol Vis Sci 59:2212-2221
Kim, Sang Jin; Port, Alexander D; Swan, Ryan et al. (2018) Retinopathy of prematurity: a review of risk factors and their clinical significance. Surv Ophthalmol 63:618-637
Adamus, Grazyna (2018) Are Anti-Retinal Autoantibodies a Cause or a Consequence of Retinal Degeneration in Autoimmune Retinopathies? Front Immunol 9:765
Watson, Spencer S; Dane, Mark; Chin, Koei et al. (2018) Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes. Cell Syst 6:329-342.e6
Windsor, Matthew A; Sun, Sissi J J; Frick, Kevin D et al. (2018) Estimating Public and Patient Savings From Basic Research-A Study of Optical Coherence Tomography in Managing Antiangiogenic Therapy. Am J Ophthalmol 185:115-122
Shahidi, Mahnaz; Felder, Anthony E; Tan, Ou et al. (2018) Retinal Oxygen Delivery and Metabolism in Healthy and Sickle Cell Retinopathy Subjects. Invest Ophthalmol Vis Sci 59:1905-1909
Hirji, Nashila; Bradley, Patrick D; Li, Shuning et al. (2018) Jalili Syndrome: Cross-sectional and Longitudinal Features of Seven Patients With Cone-Rod Dystrophy and Amelogenesis Imperfecta. Am J Ophthalmol 188:123-130
McGill, Trevor J; Stoddard, Jonathan; Renner, Lauren M et al. (2018) Allogeneic iPSC-Derived RPE Cell Graft Failure Following Transplantation Into the Subretinal Space in Nonhuman Primates. Invest Ophthalmol Vis Sci 59:1374-1383

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