Abstract

? LARGE ANIMAL CORE The Large Animal Core (LAC) provides a wide spectrum of support to vision scientists who are investigating fundamental processes and therapeutic strategies in large animal models. The Core comprises an AAALAC- accredited, fully equipped microsurgical suite and three advanced imaging suites. The LAC provides ocular imaging instrumentation, including multiple SD-OCTs, multiple electroretinography units, confocal biomicroscopy, digital slit lamps, tonometers, pachymeters, external digital SLR cameras, fundus cameras, and a Pentacam imaging system. The LAC will also provide expert technical support to help investigators understand the Core technologies and their capabilities, develop appropriate study designs, perform procedures and/or collect data. The LAC will stimulate collaboration among vision scientists by providing support for innovative multidisciplinary research, and it will support early-career vision scientists as they set up their laboratories and collect data essential for future NEI grant applications.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY012576-21
Application #
9795058
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2019-07-01
Budget End
2020-06-30
Support Year
21
Fiscal Year
2019
Total Cost
Indirect Cost

  Institution

Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618

  Publications

Partida, Gloria J; Fasoli, Anna; Fogli Iseppe, Alex et al. (2018) Autophosphorylated CaMKII Facilitates Spike Propagation in Rat Optic Nerve. J Neurosci 38:8087-8105
Swarup, Aditi; Bell, Brent A; Du, Jianhai et al. (2018) Deletion of GLUT1 in mouse lens epithelium leads to cataract formation. Exp Eye Res 172:45-53
Kowalchuk, Angelica M; Maurer, Kate A; Shoja-Taheri, Farnaz et al. (2018) Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis. Dev Biol 442:220-235
Usrey, W Martin; Sherman, S Murray (2018) Corticofugal circuits: Communication lines from the cortex to the rest of the brain. J Comp Neurol :
Failor, Samuel Wilson; Ng, Arash; Cheng, Hwai-Jong (2018) Monocular enucleation alters retinal waves in the surviving eye. Neural Dev 13:4
Yiu, Glenn; Wang, Zhe; Munevar, Christian et al. (2018) Comparison of chorioretinal layers in rhesus macaques using spectral-domain optical coherence tomography and high-resolution histological sections. Exp Eye Res 168:69-76
Smit-McBride, Zeljka; Nguyen, Johnny; Elliott, Garrett W et al. (2018) Effects of aging and environmental tobacco smoke exposure on ocular and plasma circulatory microRNAs in the Rhesus macaque. Mol Vis 24:633-646
Alitto, Henry J; Rathbun, Daniel L; Fisher, Tucker G et al. (2018) Contrast gain control and retinogeniculate communication. Eur J Neurosci :
Budamagunta, M S; Guo, F; Sun, N et al. (2018) Production of recombinant human tektin 1, 2, and 4 and in vitro assembly of human tektin 1. Cytoskeleton (Hoboken) 75:3-11
Azimi, Mina; Le, Tien T; Brown, Nadean L (2018) Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens. Differentiation 102:40-52

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