Abstract

CORE 2: PATHOLOGY AND IN VITRO IMAGING ABSTRACT The goal of the Imaging and Pathology core is to enable investigators to obtain state-of-the art imaging procedures to meet their research goals. Specifically, the module (1) provides tissue processing services for both light and electron microscopy, (2) provides access to expensive imaging equipment located in institutional core facilities and in our Cores, (3) maintains image acquisition instruments and (4) trains eye and vision researchers on how to use and develop novel imaging technologies for their individual and collaborative research programs. It is also responsible for the collection and maintenance of tissue specimens and cell lines.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY016665-11
Application #
9152461
Study Section
Special Emphasis Panel (ZEY1-VSN (03))
Project Start
Project End
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
11
Fiscal Year
2016
Total Cost
$176,228
Indirect Cost
$61,046

  Institution

Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715

  Publications

Gurel, Zafer; Sheibani, Nader (2018) O-Linked ?-N-acetylglucosamine (O-GlcNAc) modification: a new pathway to decode pathogenesis of diabetic retinopathy. Clin Sci (Lond) 132:185-198
Tan, Junkai; Fan, Ning; Wang, Ningli et al. (2018) Effects of Lentivirus-Mediated C3 Expression on Trabecular Meshwork Cells and Intraocular Pressure. Invest Ophthalmol Vis Sci 59:4937-4944
Saghiri, Mohammad Ali; Asatourian, Armen; Sheibani, Nader (2018) Angiogenesis and the prevention of alveolar osteitis: a review study. J Korean Assoc Oral Maxillofac Surg 44:93-102
Saghiri, Mohammad Ali; Asatourian, Armen; Sorenson, Christine M et al. (2018) Mice dental pulp and periodontal ligament endothelial cells exhibit different proangiogenic properties. Tissue Cell 50:31-36
Farnoodian, Mitra; Sorenson, Christine M; Sheibani, Nader (2018) PEDF expression affects the oxidative and inflammatory state of choroidal endothelial cells. Am J Physiol Cell Physiol 314:C456-C472
Haruta, Miyoshi; Tan, Li Xuan; Bushey, Daniel B et al. (2018) Environmental and Genetic Factors Regulating Localization of the Plant Plasma Membrane H+-ATPase. Plant Physiol 176:364-377
Cortese, Giuseppe P; Olin, Andrew; O'Riordan, Kenneth et al. (2018) Environmental enrichment improves hippocampal function in aged rats by enhancing learning and memory, LTP, and mGluR5-Homer1c activity. Neurobiol Aging 63:1-11
Tomasini-Johansson, Bianca R; Zbyszynski, Pawel W; Toraason, Inger et al. (2018) PEGylated pUR4/FUD peptide inhibitor of fibronectin fibrillogenesis decreases fibrosis in murine Unilateral Ureteral Obstruction model of kidney disease. PLoS One 13:e0205360
Zbyszynski, Pawel; Tomasini-Johansson, Bianca R; Peters, Donna M et al. (2018) Characterization of the PEGylated Functional Upstream Domain Peptide (PEG-FUD): a Potent Fibronectin Assembly Inhibitor with Potential as an Anti-Fibrotic Therapeutic. Pharm Res 35:126
Kaur, Gulpreet; Tan, Li Xuan; Rathnasamy, Gurugirijha et al. (2018) Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration. Proc Natl Acad Sci U S A 115:9014-9019

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