Abstract

Computational Ophthalmology Core The Computational Ophthalmology Core provides high-performance computing resources and state-of-the- art custom computer programming to UCSD vision researchers completing cellular, animal, and human vision research studies. The data analysis requirements of the vision research community are increasing exponentially as high resolution retinal imaging datasets become the standard, and genomics research utilizes exome and whole genome sequencing. The powerful CPU and GPU computational condo clusters managed by the San Diego Supercomputer Center, the immersive 3-D visualization facility, and custom software tools provided by this core facilitate analysis of these large datasets. The Computational Ophthalmology core also supports a computer programmer with image analysis and signal processing expertise to develop image analysis software toolkits, and to support computational analyses of both basic science and clinical vision research projects. In addition, essential IT services such as automated off-site backup, fileservers for secure file-sharing and institutional software licenses (MATLAB, FilemakerPro, Github, FreezerPro) are provided by the Computational Ophthalmology Core to the UCSD vision research community.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
2P30EY022589-06A1
Application #
9573254
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2018-08-01
Budget End
2019-06-30
Support Year
6
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
University of California, San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Hou, Huiyuan; Moghimi, Sasan; Zangwill, Linda M et al. (2018) Inter-eye Asymmetry of Optical Coherence Tomography Angiography Vessel Density in Bilateral Glaucoma, Glaucoma Suspect, and Healthy Eyes. Am J Ophthalmol 190:69-77
Chekuri, Anil; Guru, Aditya A; Biswas, Pooja et al. (2018) IFT88 mutations identified in individuals with non-syndromic recessive retinal degeneration result in abnormal ciliogenesis. Hum Genet 137:447-458
Hou, Huiyuan; Shoji, Takuhei; Zangwill, Linda M et al. (2018) Progression of Primary Open-Angle Glaucoma in Diabetic and Nondiabetic Patients. Am J Ophthalmol 189:1-9
Ramkumar, Hema L; Nguyen, Brian; Bartsch, Dirk-Uwe et al. (2018) REDUCED GANGLION CELL VOLUME ON OPTICAL COHERENCE TOMOGRAPHY IN PATIENTS WITH GEOGRAPHIC ATROPHY. Retina 38:2159-2167
Muftuoglu, Ilkay Kilic; Alam, Mostafa; You, Qi Sheng et al. (2018) LONG-TERM REMISSION OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION WITH AS-NEEDED ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY. Retina 38:516-522
Bosse, Brandon; Damle, Samir; Akinin, Abraham et al. (2018) In Vivo Photovoltaic Performance of a Silicon Nanowire Photodiode-Based Retinal Prosthesis. Invest Ophthalmol Vis Sci 59:5885-5892
Mundae, Rusdeep S; Zangwill, Linda M; Kabbara, Sami W et al. (2018) A Longitudinal Analysis of Peripapillary Choroidal Thinning in Healthy and Glaucoma Subjects. Am J Ophthalmol 186:89-95
Wu, Zhichao; Medeiros, Felipe A; Weinreb, Robert N et al. (2018) Performance of the 10-2 and 24-2 Visual Field Tests for Detecting Central Visual Field Abnormalities in Glaucoma. Am J Ophthalmol 196:10-17
Manalastas, Patricia Isabel C; Belghith, Akram; Weinreb, Robert N et al. (2018) Automated Beta Zone Parapapillary Area Measurement to Differentiate Between Healthy and Glaucoma Eyes. Am J Ophthalmol 191:140-148
Shim, Myoung Sup; Kim, Keun-Young; Noh, Mark et al. (2018) Optineurin E50K triggers BDNF deficiency-mediated mitochondrial dysfunction in retinal photoreceptor cell line. Biochem Biophys Res Commun 503:2690-2697

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