Abstract

- Administrative Core This core provides the administrative leadership, management and oversight of the ALS-ENABLE Resource. The Resource Director will provide budget oversight for the whole project, set the scientific goals for the whole program in collaboration with the deputy directors and Component leads, ensure milestones are met in a timely manner, assess the progress in the individual Components, make significant changes in resource composition if necessary, and report progress to NIH staff. The Administrative Core will oversee the development of a web- portal, which will serve as a single point of contact for users of all the crystallography beamlines and the bioSAXS beamline at the ALS.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Center Core Grants (P30)
Project #
1P30GM124169-01
Application #
9370113
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2017-09-01
Budget End
2018-07-31
Support Year
1
Fiscal Year
2017
Total Cost
Indirect Cost

  Institution

Name
Lawrence Berkeley National Laboratory
Department
Type
DUNS #
078576738
City
Berkeley
State
CA
Country
United States
Zip Code
94720

  Publications

Schneidman-Duhovny, Dina; Hammel, Michal (2018) Modeling Structure and Dynamics of Protein Complexes with SAXS Profiles. Methods Mol Biol 1764:449-473
Hurlburt, Nicholas K; Chen, Li-Hung; Stergiopoulos, Ioannis et al. (2018) Structure of the Cladosporium fulvum Avr4 effector in complex with (GlcNAc)6 reveals the ligand-binding mechanism and uncouples its intrinsic function from recognition by the Cf-4 resistance protein. PLoS Pathog 14:e1007263
Zhang, Shao-Qing; Chino, Marco; Liu, Lijun et al. (2018) De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles. J Am Chem Soc 140:1294-1304
Chin, S Michael; Kimberlin, Christopher R; Roe-Zurz, Zygy et al. (2018) Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab. Nat Commun 9:4679
De-la-Torre, Pedro; Choudhary, Deepanshu; Araya-Secchi, Raul et al. (2018) A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15. Biophys J 115:2368-2385
Hjortness, Michael K; Riccardi, Laura; Hongdusit, Akarawin et al. (2018) Abietane-Type Diterpenoids Inhibit Protein Tyrosine Phosphatases by Stabilizing an Inactive Enzyme Conformation. Biochemistry 57:5886-5896
Ogorzalek, Tadeusz L; Hura, Greg L; Belsom, Adam et al. (2018) Small angle X-ray scattering and cross-linking for data assisted protein structure prediction in CASP 12 with prospects for improved accuracy. Proteins 86 Suppl 1:202-214
Criglar, Jeanette M; Anish, Ramakrishnan; Hu, Liya et al. (2018) Phosphorylation cascade regulates the formation and maturation of rotaviral replication factories. Proc Natl Acad Sci U S A 115:E12015-E12023
Blaisse, Michael R; Fu, Beverly; Chang, Michelle C Y (2018) Structural and Biochemical Studies of Substrate Selectivity in Ascaris suum Thiolases. Biochemistry 57:3155-3166
Hu, Liya; Sankaran, Banumathi; Laucirica, Daniel R et al. (2018) Glycan recognition in globally dominant human rotaviruses. Nat Commun 9:2631

Showing the most recent 10 out of 18 publications