The Biometry Core of the Kennedy Center provides statistical expertise and collaboration to Center investigators on all phases of clinical, observational, and basic science research. This includes guidance on study design, study conduct, data analysis, and the interpretation as well as publication of results. ? ? The specific objectives of the Biometry Core are: (1) to assist and collaborate with Kennedy Center investigators in the design, conduct, analysis, interpretation, and reporting of clinical, translational, basic science, and observational studies; (2) to collaborate on new research initiatives and the development of applications for peer-reviewed funding; (3) to provide statistical expertise in the analysis of gene expression studies; (4) to provide guidance in the design and management of study databases; (5) to develop new statistical approaches as needed to meet specific study needs; and (6) to educate and train Kennedy Center members in study design and the statistical principles of biomedical research. ? ? In addressing these objectives, the Biometry Core strives to create a truly collaborative environment that promotes mutually productive interactions between biostatisticians and Center investigators, with the ultimate goal of enhancing the quality and productivity of the research conducted at the Kennedy Center. ? ?

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
3P30HD001799-40S1
Application #
6816633
Study Section
Special Emphasis Panel (ZHD1-MRG-C (27))
Program Officer
Vitkovic, Ljubisa
Project Start
1997-08-01
Project End
2005-06-30
Budget Start
2004-08-20
Budget End
2005-06-30
Support Year
40
Fiscal Year
2004
Total Cost
$147,832
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Miscellaneous
Type
Schools of Medicine
DUNS #
110521739
City
Bronx
State
NY
Country
United States
Zip Code
10461
Qureshi, Irfan A; Mehler, Mark F (2014) Epigenetic mechanisms underlying the pathogenesis of neurogenetic diseases. Neurotherapeutics 11:708-20
Qureshi, Irfan A; Mehler, Mark F (2014) Epigenetics of sleep and chronobiology. Curr Neurol Neurosci Rep 14:432
Qureshi, Irfan A; Mehler, Mark F (2014) An evolving view of epigenetic complexity in the brain. Philos Trans R Soc Lond B Biol Sci 369:
Qureshi, Irfan A; Mehler, Mark F (2014) Sex, epilepsy, and epigenetics. Neurobiol Dis 72 Pt B:210-6
Nguyen, Giang D; Gokhan, Solen; Molero, Aldrin E et al. (2014) The role of H1 linker histone subtypes in preserving the fidelity of elaboration of mesendodermal and neuroectodermal lineages during embryonic development. PLoS One 9:e96858
Qureshi, Irfan A; Mehler, Mark F (2013) Epigenetic mechanisms governing the process of neurodegeneration. Mol Aspects Med 34:875-82
Qureshi, Irfan A; Mehler, Mark F (2012) Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease. Nat Rev Neurosci 13:528-41
Nalavadi, Vijayalaxmi C; Muddashetty, Ravi S; Gross, Christina et al. (2012) Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation. J Neurosci 32:2582-7
Qureshi, Irfan A; Mehler, Mark F (2011) Non-coding RNA networks underlying cognitive disorders across the lifespan. Trends Mol Med 17:337-46
Qureshi, Irfan A; Mehler, Mark F (2011) Alu transcription: a rheostat for stem cell aging? Cell Cycle 10:3820-1

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