The Baylor College of Medicine Center for Reproductive Biology Research is a goal-oriented Population Research Center, dedicated to innovative basic research into mechanisms involved in regulation of mammalian reproductive processes at the cell, physiological and molecular levels. The Center has created a rich environment fostering basic research of the highest quality, and fostering interdisciplinary exchanges and contacts suitable for further studies in this important area of biomedical science. The basic science interests of participating faculty involve all aspects of modem reproductive biology research, including steroid and peptide hormones, the ovary, testis, central nervous system, and approaches ranging from endocrine physiology to gene structure, function and regulation. Although concentrated in the Cell Biology Department, the Center has wide visibility in the local research environment, through its seminar, visitor and materials distribution functions. The Center operates ten research excellence Core Laboratories, making available to scientists conducting reproductive research the most rigorous and up-- to-date methodology and resources. These laboratories are directed by skilled and experienced research faculty members, all of whom are themselves innovative investigators in reproductive biology. The Center attempts through its unique setting in the Texas Medical Center to be a focus for interaction between basic scientists and the clinical investigators. A further goal is to apply new information and insights into new approaches to contraceptive development, to problems of infertility, and to problems arising from genetic disorders common to reproduction.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
2P30HD007495-21
Application #
3102853
Study Section
Population Research Committee (HDPR)
Project Start
1978-06-01
Project End
1998-03-31
Budget Start
1993-05-01
Budget End
1994-03-31
Support Year
21
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Piyarathna, Danthasinghe Waduge Badrajee; Rajendiran, Thekkelnaycke M; Putluri, Vasanta et al. (2018) Distinct Lipidomic Landscapes Associated with Clinical Stages of Urothelial Cancer of the Bladder. Eur Urol Focus 4:907-915
Choi, Byung-Kwon; Dayaram, Tajhal; Parikh, Neha et al. (2018) Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2. Proc Natl Acad Sci U S A 115:10666-10671
Parikh, Neha; Shuck, Ryan L; Gagea, Mihai et al. (2018) Enhanced inflammation and attenuated tumor suppressor pathways are associated with oncogene-induced lung tumors in aged mice. Aging Cell 17:
Kotlajich, Matthew V; Xia, Jun; Zhai, Yin et al. (2018) Fluorescent fusions of the N protein of phage Mu label DNA damage in living cells. DNA Repair (Amst) 72:86-92
Szafran, Adam T; Stossi, Fabio; Mancini, Maureen G et al. (2017) Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis. PLoS One 12:e0180141
Ha, Kyungsoo; Ma, Chengxian; Lin, Han et al. (2017) The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites. Nat Commun 8:15751
Roarty, K; Pfefferle, A D; Creighton, C J et al. (2017) Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression. Oncogene 36:5958-5968
Aagaard, Kjersti M; Lahon, Anismrita; Suter, Melissa A et al. (2017) Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. Sci Rep 7:41389
Szafran, Adam T; Stephan, Cliff; Bolt, Michael et al. (2017) High-Content Screening Identifies Src Family Kinases as Potential Regulators of AR-V7 Expression and Androgen-Independent Cell Growth. Prostate 77:82-93
Tsai, Wei-Chih; Reineke, Lucas C; Jain, Antrix et al. (2017) Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1. J Biol Chem 292:18886-18896

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