Abstract

DESCRITION: The Study Design and Statistical Analysis Core provides services in three general areas: Study Design, Data Management, and Statistical Analysis. Within each of these areas a variety of essential services are offered. These include services traditionally offered by a core of this type, such as assistance with power and sample size determination, development of case report forms, design of data bases, training investigators in the use of hardware and software, and varying levels of assistance with statistical analyses. In addition, the Core offers services related to bioethics to ensure that human subjects concerns are appropriately addressed prior to submission to IRS review.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD026979-13
Application #
6659307
Study Section
Project Start
2002-07-01
Project End
2003-06-30
Budget Start
Budget End
Support Year
13
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
Children's Hospital of Philadelphia
Department
Type
DUNS #
073757627
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Kohls, Gregor; Antezana, Ligia; Mosner, Maya G et al. (2018) Altered reward system reactivity for personalized circumscribed interests in autism. Mol Autism 9:9
Yerys, Benjamin E; Herrington, John D; Bartley, Gregory K et al. (2018) Arterial spin labeling provides a reliable neurobiological marker of autism spectrum disorder. J Neurodev Disord 10:32
Maddox, Brenna B; Cleary, Patrick; Kuschner, Emily S et al. (2018) Lagging skills contribute to challenging behaviors in children with autism spectrum disorder without intellectual disability. Autism 22:898-906
Chapman, Kimberly A; Ostrovsky, Julian; Rao, Meera et al. (2018) Propionyl-CoA carboxylase pcca-1 and pccb-1 gene deletions in Caenorhabditis elegans globally impair mitochondrial energy metabolism. J Inherit Metab Dis 41:157-168
Yerys, Benjamin E; Herrington, John D; Satterthwaite, Theodore D et al. (2017) Globally weaker and topologically different: resting-state connectivity in youth with autism. Mol Autism 8:39
Parish-Morris, Julia; Liberman, Mark Y; Cieri, Christopher et al. (2017) Linguistic camouflage in girls with autism spectrum disorder. Mol Autism 8:48
Glauser, Tracy A; Holland, Katherine; O'Brien, Valerie P et al. (2017) Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy. Ann Neurol 81:444-453
Herrington, John D; Maddox, Brenna B; McVey, Alana J et al. (2017) Negative Valence in Autism Spectrum Disorder: The Relationship Between Amygdala Activity, Selective Attention, and Co-occurring Anxiety. Biol Psychiatry Cogn Neurosci Neuroimaging 2:510-517
Monnerie, Hubert; Romer, Micah; Jensen, Brigid K et al. (2017) Reduced sterol regulatory element-binding protein (SREBP) processing through site-1 protease (S1P) inhibition alters oligodendrocyte differentiation in vitro. J Neurochem 140:53-67
Bangasser, D A; Dong, H; Carroll, J et al. (2017) Corticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer's disease-related signaling. Mol Psychiatry 22:1126-1133

Showing the most recent 10 out of 318 publications