Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Center Core Grants (P30)
Project #
5P30HD028836-05
Application #
2025349
Study Section
Special Emphasis Panel (SRC (04))
Project Start
1992-04-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1998-08-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Children's Hosp Pittsburgh/Upmc Health Sys
Department
Type
DUNS #
044304145
City
Pittsburgh
State
PA
Country
United States
Zip Code
15224
Lane, R H; Kelley, D E; Ritov, V H et al. (2001) Altered expression and function of mitochondrial beta-oxidation enzymes in juvenile intrauterine-growth-retarded rat skeletal muscle. Pediatr Res 50:83-90
Lane, R H; Ramirez, R J; Tsirka, A E et al. (2001) Uteroplacental insufficiency lowers the threshold towards hypoxia-induced cerebral apoptosis in growth-retarded fetal rats. Brain Res 895:186-93
Lane, R H; Kelley, D E; Gruetzmacher, E M et al. (2001) Uteroplacental insufficiency alters hepatic fatty acid-metabolizing enzymes in juvenile and adult rats. Am J Physiol Regul Integr Comp Physiol 280:R183-90
Tsirka, A E; Gruetzmacher, E M; Kelley, D E et al. (2001) Myocardial gene expression of glucose transporter 1 and glucose transporter 4 in response to uteroplacental insufficiency in the rat. J Endocrinol 169:373-80
Clark RSB; Chen, M; Kochanek, P M et al. (2001) Detection of single- and double-strand DNA breaks after traumatic brain injury in rats: comparison of in situ labeling techniques using DNA polymerase I, the Klenow fragment of DNA polymerase I, and terminal deoxynucleotidyl transferase. J Neurotrauma 18:675-89
Lane, R H; Tsirka, A E; Gruetzmacher, E M (2000) Uteroplacental insufficiency alters cerebral mitochondrial gene expression and DNA in fetal and juvenile rats. Pediatr Res 47:792-7
Clark, R S; Kochanek, P M; Adelson, P D et al. (2000) Increases in bcl-2 protein in cerebrospinal fluid and evidence for programmed cell death in infants and children after severe traumatic brain injury. J Pediatr 137:197-204
Clark, R S; Kochanek, P M; Chen, M et al. (1999) Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury. FASEB J 13:813-21
Witchel, S F; Lee, P A (1998) Human chorionic gonadotropin stimulation to assess for ovarian hyperandrogenism. J Pediatr Adolesc Gynecol 11:73-8
Witchel, S F; Lee, P A (1998) Identification of heterozygotic carriers of 21-hydroxylase deficiency: sensitivity of ACTH stimulation tests. Am J Med Genet 76:337-42

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