The Biostatistics Core of the North Carolina Center for AIDS Research will provide integrated collaborative services and expertise in statistical methodology to HFV/AIDS researchers conducting basic, clinical, behavioral, translational, and epidemiologic studies. The Core will offer a high level of expertise and experience for addressing the more complex statistical issues and tasks faced by CFAR investigators. Adaptive administration of Core funds will ensure responsiveness to research needs. Some of its most important activities will contribute to study design in new protocols and in appropriate statistical analysis of existing data. The Core will make full advantage of existing infrastructure and local faculty renowned for their expertise in specialized fields of statistical science. The primary personnel of the Biostatistics Core have worked together for many years providing statistical collaboration via core units and coordinating centers. The Biostatistics Core will work in concert with the Administrative, Developmental, Clinical/Behavioral, Virology, and Pharmacology Cores to ensure coordination of efforts and provide economy of scale at every opportunity. During its first year of CFAR research, The Biostatistics Core will seek a high level of productivity by proactively engaging investigators in identification and delivery of essential collaborative services. Through years of experience the key personnel of the Core have well-developed operational procedures and highly productive computer facilities that will be immediately in operation of the centrally located School of Public Health complex.

Project Start
2000-08-01
Project End
2001-07-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
3
Fiscal Year
2000
Total Cost
$244,002
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Wohl, David A; Khan, Maria R; Tisdale, Caroline et al. (2011) Locating the places people meet new sexual partners in a southern US city to inform HIV/STI prevention and testing efforts. AIDS Behav 15:283-91
Cohen, Myron S; Gay, Cynthia L (2010) Treatment to prevent transmission of HIV-1. Clin Infect Dis 50 Suppl 3:S85-95
Anderson, Jeffrey A; Jiang, Hongyu; Ding, Xiao et al. (2008) Genotypic susceptibility scores and HIV type 1 RNA responses in treatment-experienced subjects with HIV type 1 infection. AIDS Res Hum Retroviruses 24:685-94
Edwards, Lloyd J; Stewart, Paul W; MacDougall, James E et al. (2006) A method for fitting regression splines with varying polynomial order in the linear mixed model. Stat Med 25:513-27
Graham, Jinko; McNeney, Brad; Seillier-Moiseiwitsch, Francoise (2005) Stepwise detection of recombination breakpoints in sequence alignments. Bioinformatics 21:589-95
Esther Jr, Charles R; Henry, Marianna M; Molina, Paul L et al. (2005) Nontuberculous mycobacterial infection in young children with cystic fibrosis. Pediatr Pulmonol 40:39-44
Meeker, Rick B; Boles, Jeramiah C; Robertson, Kevin R et al. (2005) Cerebrospinal fluid from human immunodeficiency virus--infected individuals facilitates neurotoxicity by suppressing intracellular calcium recovery. J Neurovirol 11:144-56
Baldewicz, Teri T; Leserman, Jane; Silva, Susan G et al. (2004) Changes in neuropsychological functioning with progression of HIV-1 infection: results of an 8-year longitudinal investigation. AIDS Behav 8:345-55
Thorpe, Joshua M; Smith, Scott R; Trygstad, Troy K (2004) Trends in emergency department antibiotic prescribing for acute respiratory tract infections. Ann Pharmacother 38:928-35
Meeker, R B; Boles, J C; Bragg, D C et al. (2004) Development of neuronal sensitivity to toxins in cerebrospinal fluid from HIV-type 1-infected individuals. AIDS Res Hum Retroviruses 20:1072-86

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