The overarching theme of the HIV Center ? The Science of Ending the HIV/AIDS Epidemic (EtE): Efficacy to Effectiveness ? demands innovative study designs and state-of-the-art analytic strategies. These include rigorously designed trials to evaluate prevention interventions and treatment paradigms among the most vulnerable populations in single-site or multi-site studies and implementation trials in which strategies for scale- up at the community level may be evaluated. Also critical are public-health scale trend analyses of epidemiologic surveillance data, social network analyses, and service utilization studies. Moreover, qualitative and quantitative assessment methodologies, including mixed methods, can provide key insights into a) challenges faced by high risk populations in reducing risk behavior and using HIV services; b) contexts of emergent risk situations; and c) case studies of treatment successes or failures. The Statistics, Assessment, and Data Management (StAD) Core will be a resource for cutting-edge conceptualization, consultation, and collaboration in major research methods critical to the Center's mission. The Core has three Specific Aims: (1) to develop and promote state-of-the-art research design and analytic strategies for study planning, analytic monitoring, and statistical analyses in bio-behavioral HIV/AIDS research; (2) to facilitate identification, adaptation, and/or development of assessment strategies that maximize validity, technological currency and flexibility, and explanatory power; and 3) to promote rigorous data management. To achieve these aims, the StAD Core will implement a coordinated set of activities including triaged individual consultation on developing proposals, funded studies, and manuscripts; expert monitored analytical and data management support; participation in Cross-Core Meeting reviews; and didactic capacity-building activities, including seminars and workshops. In addition to providing intensive guidance on research designs, statistical approaches and assessment, we will leverage expertise in our institutional data management center to provide access to a state-of-the-art data management system that ensures and optimizes secure data collection, including real-time data quality checks and storage, and will build capacity for harmonizing existing and new data sets to enable meta-analyses, pooled analyses, pilot study research, and data sharing. StAD Core Members have complementary expertise in the design and conduct of clinical and behavioral intervention trials, the determinants studies that inform them, and state-of-the-art analytical strategies and data management systems. Core Director, Martina Pavlicova, Ph.D., an Associate Professor of Biostatistics at the Columbia University Mailman School of Public Health has experience overseeing statistical teams on HIV clinical trials and observational studies. Core Co-Director, Susan Tross, Ph.D., a long-time member of the Center is an Associate Professor in the Department of Psychiatry at NYSPI and Columbia University with expertise in assessing, developing and evaluating substance use and HIV risk interventions.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH043520-33
Application #
10090637
Study Section
Special Emphasis Panel (ZMH1)
Project Start
1987-09-30
Project End
2023-01-31
Budget Start
2021-02-01
Budget End
2022-01-31
Support Year
33
Fiscal Year
2021
Total Cost
Indirect Cost
Name
New York State Psychiatric Institute
Department
Type
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Balán, Iván C; Frasca, Timothy; Dolezal, Curtis et al. (2018) HIV Risk Reduction by Avoiding Sex With Partners Unwilling to Undergo HIV Testing Is Not Coercion. J Acquir Immune Defic Syndr 78:e38
Brown 3rd, William; Giguere, Rebecca; Sheinfil, Alan et al. (2018) Challenges and solutions implementing an SMS text message-based survey CASI and adherence reminders in an international biomedical HIV PrEP study (MTN 017). J Biomed Inform 80:78-86
Benson, Stephanie; Elkington, Katherine S; Leu, Cheng-Shiun et al. (2018) Association Between Psychiatric Disorders, Substance Use, and Sexual Risk Behaviors in Perinatally HIV-Exposed Youth. J Assoc Nurses AIDS Care 29:538-549
Kelvin, Elizabeth A; George, Gavin; Mwai, Eva et al. (2018) Offering self-administered oral HIV testing to truck drivers in Kenya to increase testing: a randomized controlled trial. AIDS Care 30:47-55
Balán, Iván C; Giguere, Rebecca; Brown 3rd, William et al. (2018) Brief Participant-Centered Convergence Interviews Integrate Self-Reports, Product Returns, and Pharmacokinetic Results to Improve Adherence Measurement in MTN-017. AIDS Behav 22:986-995
Parcesepe, Angela M; Tymejczyk, Olga; Remien, Robert et al. (2018) Psychological distress, health and treatment-related factors among individuals initiating ART in Oromia, Ethiopia. AIDS Care 30:338-342
Iribarren, Sarah J; Ghazzawi, Alhasan; Sheinfil, Alan Z et al. (2018) Mixed-Method Evaluation of Social Media-Based Tools and Traditional Strategies to Recruit High-Risk and Hard-to-Reach Populations into an HIV Prevention Intervention Study. AIDS Behav 22:347-357
Barnes, David M; Des Jarlais, Don C; Wolff, Margaret et al. (2018) A qualitative study of persons who inject drugs but who have never helped others with first injections: how their views on helping contrast with the views of persons who have helped with first injections, and implications for interventions. Harm Reduct J 15:43
Masvawure, Tsitsi B; Mantell, Joanne E; Tocco, Jack Ume et al. (2018) Intentional and Unintentional Condom Breakage and Slippage in the Sexual Interactions of Female and Male Sex Workers and Clients in Mombasa, Kenya. AIDS Behav 22:637-648
Zhang, Yinfeng; Fogel, Jessica M; Guo, Xu et al. (2018) Antiretroviral drug use and HIV drug resistance among MSM and transgender women in sub-Saharan Africa. AIDS 32:1301-1306

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