Combination Prevention is the integration of behavioral and biomedical strategies to address HIV, especially structural approaches Building on 25 years of knowledge accumulated with efficacious behavioral interventions, structural approaches create access, settings, policies, or community level applications of learned principles to advance prevention, detection, and care^. The CHIPTS Combination Prevention Core (previously, the Intervention Core) has reorganized its mission, partners, and outcome markers to emphasize structural, biomedical, information technology, social media and behavioral innovations. Three major trends demand this realignment. First, HIV prevention, including combination prevention is significantly influenced by the global economic recession. Inadequate resources will force 22 countries to disrupt antiretroviral (ARV) treatments for persons living with HIV. The largest cuts in donor funding have been to the 34 countries carrying 75% of disease burden^ California cut its HIV budget by $82 million in fiscal year 2009-10. Los Angeles County"""""""" halved its prevention budget, and reduced HIV care by a third. This fiscal environment requires smarter, more cost-effective intervention strategies that can be broadly diffused. Second, domestically, HIV is predominantly a disease of ethnic minority men who have sex with men (MSM). Black MSM are overrepresented among persons living with HIV (PLH) PLH;18% of LA County cases are African American, while African Americans are only 4.7% of the County's populafion.* Latino (32%) and White, non Latino (47%) MSM are also impacted. Both aging MSM (>50 years;both HIV+ and HIV-) and younger MSM (<30 years) have been saturated with HIV prevention messages, yet incidence continues to rise in these groups, highlighting need for innovative delivery modalities and messages. The Core's reorganization responds to these risks among MSM, especially in Los Angeles. Third, HIV services have been vertically integrated in specialty settings;now advocates are lobbying for horizontally integrated systems for comprehensive care delivery. The health priorities that compete with HIV, especially other chronic health conditions, are gaining attention. Domestically, the patient-centered medical home in health care reform will transform HIV care. Our prevention and intervention models must be adapted to respond to these trends. The CHIPTS'Combination Prevention Core will lead innovation in detection, prevention and care in response to these trends. Our interdisciplinary team is a resource for identifying, designing, and implementing structural, combination approaches for HIV prevention systems, be they local, regional, national, or global. The Core has planned a strategic approach to impact HIV burden of disease that includes: adoption of innovations and evidence-based combination interventions by health jurisdictions, networks of providers and communities of HIV care, treatment services, and consumers;implementation of collaborative combination prevention efforts with health departments that can implement and diffuse interventions in large populations;and greater engagement in research among populations identified nationally and globally with the highest need for HIV prevention, care and treatment.
The specific aims for the Combination Prevention Core are: 1. Science: Leading research in combination prevention interventions and strategies that integrate medical, technology, social media and behavioral advancements in HIV prevention and care through individual scientist driven research and participation in research networks. 2. Networking: Providing time and resources to link experts in social media, global information system-technology (GIS), on-line communication, point-of-sale diagnostics and community engagement strategies with agencies and communities at risk. We establish networks for HIV prevention research and programs among those facing highest risks for HIV transmission: communities of color, especially MSM and women at heightened sexual risk. 3. Capacity Building: Advancing the capacity of linked coalitions and networks of scientists, domestic and international health departments and ministries, and engaged non-governmental organizations (NGOs) and CBOs to launch innovative, bold, and creative interventions for impacted populations.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Center Core Grants (P30)
Project #
5P30MH058107-18
Application #
8607999
Study Section
Special Emphasis Panel (ZMH1-ERB-F)
Project Start
Project End
Budget Start
2014-02-01
Budget End
2015-01-31
Support Year
18
Fiscal Year
2014
Total Cost
$194,948
Indirect Cost
$43,057
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Li, Michael J; Frank, Heather Guentzel; Harawa, Nina T et al. (2018) Racial Pride and Condom Use in Post-Incarcerated African-American Men Who Have Sex With Men and Women: Test of a Conceptual Model for the Men in Life Environments Intervention. Arch Sex Behav 47:169-181
Allyn, P R; O'Malley, S M; Ferguson, J et al. (2018) Attitudes and potential barriers towards hepatitis C treatment in patients with and without HIV coinfection. Int J STD AIDS 29:334-340
Holloway, Ian W; Bednarczyk, Robert; Fenimore, Vincent L et al. (2018) Factors Associated with Immunization Opinion Leadership among Men Who Have Sex with Men in Los Angeles, California. Int J Environ Res Public Health 15:
Clark, Jesse L; Segura, Eddy R; Oldenburg, Catherine E et al. (2018) Traditional and Web-Based Technologies to Improve Partner Notification Following Syphilis Diagnosis Among Men Who Have Sex With Men in Lima, Peru: Pilot Randomized Controlled Trial. J Med Internet Res 20:e232
Rotheram-Borus, Mary Jane; Davis, Emily; Rezai, Roxana (2018) Stopping the rise of HIV among adolescents globally. Curr Opin Pediatr 30:131-136
Dangerfield 2nd, Derek T; Harawa, Nina T; Smith, Laramie R et al. (2018) Latent Classes of Sexual Risk Among Black Men Who Have Sex with Men and Women. Arch Sex Behav 47:2071-2080
Algarin, Angel B; Ward, Patrick J; Christian, W Jay et al. (2018) Spatial Distribution of Partner-Seeking Men Who Have Sex With Men Using Geosocial Networking Apps: Epidemiologic Study. J Med Internet Res 20:e173
Comulada, W Scott; Wynn, Adriane; van Rooyen, Heidi et al. (2018) Using mHealth to Deliver a Home-Based Testing and Counseling Program to Improve Linkage to Care and ART Adherence in Rural South Africa. Prev Sci :
Dangerfield 2nd, Derek T; Ober, Allison J; Smith, Laramie R et al. (2018) Exploring and Adapting a Conceptual Model of Sexual Positioning Practices and Sexual Risk Among HIV-Negative Black Men Who Have Sex With Men. J Sex Res 55:1022-1032
Baker, Zoƫ; Javanbakht, Marjan; Mierzwa, Stan et al. (2018) Predictors of Over-Reporting HIV Pre-exposure Prophylaxis (PrEP) Adherence Among Young Men Who Have Sex With Men (YMSM) in Self-Reported Versus Biomarker Data. AIDS Behav 22:1174-1183

Showing the most recent 10 out of 715 publications