D3.1. Rationale and Mission. The goal of the Computational Genomics Core is to provide bioinformatics supportand advanced genomics tools to neuroscientists at Tufts University and its affiliated institutions. During thefirst 1.5 years of the grant cycle, the core provided basic bioinformatics support to neuroscientists. The growingneed for both more sophisticated analytic tools and high throughput genomic technologies led to an expansionof the core over the past 2 years. Partnership with other Tufts Centers - the GRASP gastroenterology centerand the Molecular Cardiology Research Institute (MCRI) - enabled the CNR to expand the bioinformatics consultationteam as well as provide selected genomics services, including real-time RT-PCR and gene microarrayanalysis. The computational genomics team is currently led by a PhD-level computational biologist, Dr. LaxIyer and includes Mr. Christopher Parkin, who performs data analysis and consultation, and Ms. Yue Shao whosupervises the real-time PCR (Q-PCR) service and performs microarray experiments for neuroscientists.
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