Abstract

IMAGE AND SPECTROSCOPY ANALYSIS AND VISUALIZATION CORE PI: Christophe Lenglet, PhD; co-PI: Noam Harel, PhD This Core will provide advanced analysis tools and resources for a variety of neuroimaging modalities including structural MRI, High Angular Resolution Diffusion Imaging (HARDI), Diffusion Spectroscopic Imaging (DSI), functional MRI (fMRI), intrinsic relaxation parameter imaging, MR spectroscopy (MRS), as well as Positron Emission Tomography (PET) and Computed Tomography (CT). The unique needs of each of these modalities will be served through shared computing equipment, software and expert personnel in the Core. Additionally, the Core will provide support for multi-modality image analysis. Image reconstruction, analysis and visualization require sophisticated mathematical modeling and computational resources. The overall goal of this Core is to provide such unique resources for human and animal neuroimaging research. They will enable individuals to generate high-quality images from high (3 and 4T) and ultrahigh (7T and higher) field MR scanners and to efficiently analyze them through state-of-the-art methods.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Center Core Grants (P30)
Project #
5P30NS076408-04
Application #
8915762
Study Section
Special Emphasis Panel (ZNS1-SRB-R)
Project Start
Project End
2016-06-30
Budget Start
2015-07-01
Budget End
2016-06-30
Support Year
4
Fiscal Year
2015
Total Cost
$101,737
Indirect Cost
$34,805

  Institution

Name
University of Minnesota Twin Cities
Department
Type
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Adanyeguh, Isaac M; Perlbarg, Vincent; Henry, Pierre-Gilles et al. (2018) Autosomal dominant cerebellar ataxias: Imaging biomarkers with high effect sizes. Neuroimage Clin 19:858-867
Zhu, Xiao-Hong; Lu, Ming; Chen, Wei (2018) Quantitative imaging of brain energy metabolisms and neuroenergetics using in vivo X-nuclear 2H, 17O and 31P MRS at ultra-high field. J Magn Reson 292:155-170
Zhang, Simeng; Connolly, Allison T; Madden, Lauren R et al. (2018) High-resolution local field potentials measured with deep brain stimulation arrays. J Neural Eng 15:046019
Deelchand, Dinesh K; Auerbach, Edward J; Marja?ska, Ma?gorzata (2018) Apparent diffusion coefficients of the five major metabolites measured in the human brain in vivo at 3T. Magn Reson Med 79:2896-2901
Moerel, Michelle; De Martino, Federico; Kemper, Valentin G et al. (2018) Sensitivity and specificity considerations for fMRI encoding, decoding, and mapping of auditory cortex at ultra-high field. Neuroimage 164:18-31
Plantinga, Birgit R; Temel, Yasin; Duchin, Yuval et al. (2018) Individualized parcellation of the subthalamic nucleus in patients with Parkinson's disease with 7T MRI. Neuroimage 168:403-411
Deelchand, Dinesh K; Kantarci, Kejal; Öz, Gülin (2018) Improved localization, spectral quality, and repeatability with advanced MRS methodology in the clinical setting. Magn Reson Med 79:1241-1250
Slopsema, Julia P; Peña, Edgar; Patriat, Remi et al. (2018) Clinical deep brain stimulation strategies for orientation-selective pathway activation. J Neural Eng 15:056029
Joers, James M; Deelchand, Dinesh K; Lyu, Tianmeng et al. (2018) Neurochemical abnormalities in premanifest and early spinocerebellar ataxias. Ann Neurol 83:816-829
Deelchand, Dinesh K; Auerbach, Edward J; Kobayashi, Naoharu et al. (2018) Transverse relaxation time constants of the five major metabolites in human brain measured in vivo using LASER and PRESS at 3 T. Magn Reson Med 79:1260-1265

Showing the most recent 10 out of 177 publications