Abstract

Morphologic study of squirrel monkey placentation was done to determine if gross and microscopic abnormalities were associated with and predictive for negative fetal outcomes such as abortion and neonatal death. Fourteen complete placentas and 6 partial placentas were recovered from abortions, stillbirths, and live births. Placentas were weighed immediately, photographed, evaluated for gross lesions and sections collected for histopathology and frozen in liquid nitrogen. Three microscopic lesions have been found to be predictive for fetal/infant death: acute suppurative inflammation, nonsuppurative inflammation associated with Encephalitozoon infection, and extensive placental infarction. Microscopic evaluation of the placenta is particularly helpful when there is no fetal tissue or when lesions in the fetus are not diagnostic.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Animal (Mammalian and Nonmammalian) Model, and Animal and Biological Material Resource Grants (P40)
Project #
5P40RR001254-18
Application #
6280771
Study Section
Project Start
1998-04-01
Project End
1999-03-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
18
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
University of South Alabama
Department
Type
DUNS #
City
Mobile
State
AL
Country
United States
Zip Code
36688

  Publications

Lindo, Fiona M; Carr, Emily S; Reyes, Michelle et al. (2015) Randomized trial of cesarean vs vaginal delivery for effects on the pelvic floor in squirrel monkeys. Am J Obstet Gynecol 213:735.e1-8
Joyce, John S; Dornak, Sarah; Gendron, Jilene M et al. (2014) Lack of association between pelvic outlet diameter and pelvic organ prolapse in squirrel monkeys. Int Urogynecol J 25:1121-6
Raghanti, Mary Ann; Edler, Melissa K; Meindl, Richard S et al. (2014) Humans and great apes share increased neocortical neuropeptide Y innervation compared to other haplorhine primates. Front Hum Neurosci 8:101
Hopper, Lm; Holmes, An; Williams, LE et al. (2013) Dissecting the mechanisms of squirrel monkey (Saimiri boliviensis) social learning. PeerJ 1:e13
Freeman, Hani D; Sullivan, Jennifer; Hopper, Lydia M et al. (2013) Different responses to reward comparisons by three primate species. PLoS One 8:e76297
Raghanti, Mary Ann; Conley, Tiffini; Sudduth, Jessica et al. (2013) Neuropeptide Y-immunoreactive neurons in the cerebral cortex of humans and other haplorrhine primates. Am J Primatol 75:415-24
Blomquist, G E; Williams, L E (2013) Quantitative genetics of costly neonatal sexual size dimorphism in squirrel monkeys (Saimiri boliviensis). J Evol Biol 26:756-65
Nehete, Pramod N; Hanley, Patrick W; Nehete, Bharti P et al. (2013) Phenotypic and functional characterization of lymphocytes from different age groups of Bolivian squirrel monkeys (Saimiri boliviensis boliviensis). PLoS One 8:e79836
Hanna, Jandy B; Schmitt, Daniel (2011) Locomotor energetics in primates: gait mechanics and their relationship to the energetics of vertical and horizontal locomotion. Am J Phys Anthropol 145:43-54
Talbot, Catherine F; Freeman, Hani D; Williams, Lawrence E et al. (2011) Squirrel monkeys' response to inequitable outcomes indicates a behavioural convergence within the primates. Biol Lett 7:680-2

Showing the most recent 10 out of 61 publications