Abstract

In critically ill preterm and term infants with cardiovascular compromise, oxygen delivery fails to meet the demand of cellular oxygen consumption, and unless recognized early and treated aggressively, failure of the circulatory system is associated with increased mortality or potentially severe short/long-term morbidity [1]. There has been considerable progress in our understanding of developmental cardiovascular physiology, however there remains significant gaps in our knowledge particularly pertaining to treatment of patent ductus arteriosus (PDA).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Biotechnology Resource Grants (P41)
Project #
5P41EB001978-33
Application #
9344642
Study Section
Special Emphasis Panel (ZEB1)
Project Start
Project End
2019-08-31
Budget Start
2017-09-01
Budget End
2018-08-31
Support Year
33
Fiscal Year
2017
Total Cost
Indirect Cost

  Institution

Name
University of Southern California
Department
Type
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90033

  Publications

Armoni Domany, Keren; Hossain, Md Monir; Nava-Guerra, Leonardo et al. (2018) Cardioventilatory Control in Preterm-born Children and the Risk of Obstructive Sleep Apnea. Am J Respir Crit Care Med 197:1596-1603
Sunwoo, John; Chalacheva, Patjanaporn; Khaleel, Maha et al. (2018) A novel cross-correlation methodology for assessing biophysical responses associated with pain. J Pain Res 11:2207-2219
Park, A Young J; Wang, Joshua; Jayne, Jordanna et al. (2018) Pharmacokinetics of Tedizolid in Plasma and Sputum of Adults with Cystic Fibrosis. Antimicrob Agents Chemother 62:
Chalacheva, Patjanaporn; Khaleel, Maha; Sunwoo, John et al. (2017) Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease. PLoS One 12:e0178353
Geng, Kunling; Marmarelis, Vasilis Z (2017) Methodology of Recurrent Laguerre-Volterra Network for Modeling Nonlinear Dynamic Systems. IEEE Trans Neural Netw Learn Syst 28:2196-2208
Zhang, Yaping; Hu, Kaiqiang; Beumer, Jan H et al. (2017) RAD-ADAPT: Software for modelling clonogenic assay data in radiation biology. DNA Repair (Amst) 52:24-30
Bensman, Timothy J; Wang, Joshua; Jayne, Jordanna et al. (2017) Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Determine Optimal Dosing of Ceftazidime-Avibactam for the Treatment of Acute Pulmonary Exacerbations in Patients with Cystic Fibrosis. Antimicrob Agents Chemother 61:
Song, Gina; Pacini, Giovanni; Ahrén, Bo et al. (2017) Glucagon increases insulin levels by stimulating insulin secretion without effect on insulin clearance in mice. Peptides 88:74-79
Dolton, Michael J; D'Argenio, David Z (2017) Population-based meta-analysis of roxithromycin pharmacokinetics: dosing implications of saturable absorption and protein binding. J Antimicrob Chemother 72:1129-1136
Henley, Brandon Christian; Shin, Dae C; Zhang, Rong et al. (2017) Compartmental and Data-Based Modeling of Cerebral Hemodynamics: Nonlinear Analysis. IEEE Trans Biomed Eng 64:1078-1088

Showing the most recent 10 out of 146 publications