Abstract

The broad mission of our Center for Advanced Imaging Innovation and Research (CAI2R) is to bring together collaborative translational research teams for the development of high-impact biomedical imaging technologies, with the ultimate goal of changing day-to-day clinical practice. Technology Research and Development (TR&D) Project 3 aims to exploit unique synergies between Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET), in order to improve and inform imaging-based evaluations of tissue structure and function in disease. Using modern methods of machine learning and other enabling hardware and software, we will combine these two complementary imaging modalities much as distinct sensory modalities are combined into a multifaceted multisensory stream. Concrete outcomes of our work will include 1) new techniques and technologies for motion correction in MR and PET; 2) new algorithms for the extraction of complementary information from MR and PET acquisitions; 3) new tracers that are tailored for combined MR-PET scanning rather than merely being addressed at traditional molecular targets; and 4) new means of elucidating the intrinsic structure and function of tissue.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Biotechnology Resource Grants (P41)
Project #
5P41EB017183-07
Application #
9996681
Study Section
Special Emphasis Panel (ZEB1)
Project Start
2014-09-30
Project End
2024-07-31
Budget Start
2020-08-01
Budget End
2021-07-31
Support Year
7
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016

  Publications

Chen, Gang; Zhang, Bei; Cloos, Martijn A et al. (2018) A highly decoupled transmit-receive array design with triangular elements at 7T. Magn Reson Med 80:2267-2274
Assländer, Jakob; Cloos, Martijn A; Knoll, Florian et al. (2018) Low rank alternating direction method of multipliers reconstruction for MR fingerprinting. Magn Reson Med 79:83-96
Alon, Leeor; Lattanzi, Riccardo; Lakshmanan, Karthik et al. (2018) Transverse slot antennas for high field MRI. Magn Reson Med 80:1233-1242
Feng, Li; Delacoste, Jean; Smith, David et al. (2018) Simultaneous Evaluation of Lung Anatomy and Ventilation Using 4D Respiratory-Motion-Resolved Ultrashort Echo Time Sparse MRI. J Magn Reson Imaging :
Liu, Saifeng; Brisset, Jean-Christophe; Hu, Jiani et al. (2018) Susceptibility weighted imaging and quantitative susceptibility mapping of the cerebral vasculature using ferumoxytol. J Magn Reson Imaging 47:621-633
Leithner, Doris; Moy, Linda; Morris, Elizabeth A et al. (2018) Abbreviated MRI of the Breast: Does It Provide Value? J Magn Reson Imaging :
Khegai, Oleksandr; Madelin, Guillaume; Brown, Ryan et al. (2018) Dynamic phosphocreatine imaging with unlocalized pH assessment of the human lower leg muscle following exercise at 3T. Magn Reson Med 79:974-980
Wang, Yuan; Wang, Yao; Lui, Yvonne W (2018) Generalized Recurrent Neural Network accommodating Dynamic Causal Modeling for functional MRI analysis. Neuroimage 178:385-402
Assländer, Jakob; Glaser, Steffen J; Hennig, Jürgen (2018) Application of spin echoes in the regime of weak dephasing to T1 -mapping of the lung. Magn Reson Med 79:960-967
Rezaei, Ahmadreza; Deroose, Christophe M; Vahle, Thomas et al. (2018) Joint Reconstruction of Activity and Attenuation in Time-of-Flight PET: A Quantitative Analysis. J Nucl Med 59:1630-1635

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