This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator.Water is an important common molecule in tissues whose importance is often underestimated. The absorption spectrum of water is a sensitive marker of many important physiological conditions in tissues relevant to cancer and wound healing. We have found that near infrared diffuse optical spectroscopy is a technique that can characterize the properties of water by measuring small changes in the absorption spectrum of water in tissues. Examples of use include determining tissue temperature and bound/free water state characterization.
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