Flow cytometric analyses of continuous BrdU incorporation patterns are being performed on radiation-sensitive and radiation-resistant lines of mouse cells at periods up to 24 h following doses of gamma radiation. These studies are designed to determine the extent of the sensitivity of the mouse cell lines following the transfection of new genes into the parental cell line. We have recently demonstrated that the transfection of specific genes can increase the radiation sensitivity of some cell line at different phases in the cell cycle.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR001315-18
Application #
6327965
Study Section
Project Start
2000-07-01
Project End
2001-06-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
18
Fiscal Year
2000
Total Cost
$1,532
Indirect Cost
Name
Los Alamos National Lab
Department
Type
DUNS #
City
Los Alamos
State
NM
Country
United States
Zip Code
87545
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