We have recently discovered the utility of resonance light scattering (RLS) for the study of supramolecular assemblies of chromophores (Science 269, 935 (1995)) and especially porphyrins (J. Amer. Chem. Soc. 115, 5393 (1993)) and chlorophylls (Biophys. J. 68, 335 (1995)). We are presently using this method to aid in the determination of the size and molecular orientation of these arrays and to investigate thermodynamics and kinetic aspects of their formation. In addition, we are exploring the nature and extent of the information inherent in the RLS signals (Biophys. J., 1998, in press). As part of this effort, we wish to determine RLS lifetimes and their dependence on structural and electronic features of aggregates.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR001348-17
Application #
6281068
Study Section
Project Start
1998-08-01
Project End
1999-07-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
17
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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