Distribution of Dopamine Receptors: Parkinsons

Boyson, Sally

Abstract

The role of dopaminergic cells in Parkinson's disease makes it important to determine the neuroanatomical locus of dopamine action. To determine this, DUMAS is used to quantify autoradiograms of radiolignads bound to the dopamine receptor subtypes (D1, D2) in the rat brain

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Center for Research Resources (NCRR)
• Type: Biotechnology Resource Grants (P41)
• Project #: 5P41RR001638-11
• Application #: 5223503
• Support Year: 11
• Fiscal Year: 1996

Publications

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Ali, W S; Cohen, F S (1998) Registering coronal histological 2-D sections of a rat brain with coronal sections of a 3-D brain atlas using geometric curve invariants and B-spline representation. IEEE Trans Med Imaging 17:957-66

Shumsky, J S; Wu, Y; Murphy, E H et al. (1998) Prenatal cocaine exposure does not affect selected GABAA receptor subunit mRNA expression in rabbit visual cortex. Ann N Y Acad Sci 846:371-4

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