The SIR provided [9- 15 Nl[""""""""N-amino]adenosine; 10mg [9- 1 ladenosine; 10mg adenosine; 10mg (CAG)6; 5mg The studies undertaken here are bioanalytical studies of the feasibility of detection of vibrational mode frequency shifts in a single isotopically labeled base in a large oligomeric DNA molecule. The vibrational background due to water and the other vibrations of the oligomer serve as a background that makes difficult any interpretation of the vibrational spectrum. By specific isotopic labeling the ability to discern specific vibrational modes will be demonstrated.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR002231-14
Application #
6281460
Study Section
Project Start
1998-01-15
Project End
1999-01-14
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
14
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Los Alamos National Lab
Department
Type
DUNS #
City
Los Alamos
State
NM
Country
United States
Zip Code
87545
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