This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The global and local flexibility's of the L7/L12 domain are being investigated to identify the solution characterization of this protein. The results will be evaluated in terms of the position and orientation of the two L7/L12 domains in the complete ribosome. In addition, the postulant binding affinity of L10, a second ribosome protein, and elongation factor Tu with L7/L21 will be examined. This data should help further our understanding on how these proteins cooperate within the ribosome during a protein elongation.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
2P41RR003155-21
Application #
7357978
Study Section
Special Emphasis Panel (ZRG1-BCMB-E (41))
Project Start
2006-08-29
Project End
2007-07-31
Budget Start
2006-08-29
Budget End
2007-07-31
Support Year
21
Fiscal Year
2006
Total Cost
$8,323
Indirect Cost
Name
University of California Irvine
Department
Biomedical Engineering
Type
Schools of Engineering
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697
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