This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator.
The aim of our lab's research is to truly understand the underlying physics of light propagation in turbid media and then use the information to investigate brain tissue function during stimulation (finger tapping, etc.) and during disease (ADHD, sleep apnea, etc.). Our frequency-domain (intensity modulated) NIR spectrometers are fast, realtively inexpensive, technically simple, and most importantly, non-invasive and non-ionizing (safe). Our probes also possess novel contrast mechanisms that complement those of X-Ray, ultrasound, and MRI. The purpose of my research is to combine the use of NIR spectroscopy and other modalities in functional imaging in order to study the pathological processes of diseases that are rooted in oxygen deprivation via hypoxia and ischemia. Since we measure oxygen delivery and consumption in tissues, my aim is to develop the potential of NIRS into a screening and diagnostic clinical tool.
Showing the most recent 10 out of 200 publications
