This project involves the implementation of high temperature superconducting surface coils for use at 2 T. The main technical challenge of the project is to develop a probe which will regulate the temperature of the coils at 77 K, using liquid nitrogen as the coolant. The probe will be used to determine the effect of high Q surface coils on the signal-to-noise ratio in NMR microscopy, as well as determining what the effect of the magnetic field is on the physical characteristics of the high temperature superconducting films. The biological focus of the project is to explore the effect of field strength on contrast mechanisms. Specifically, the higher signal-to-noise ratio expected from the HTS surface coils will be utilized to image tissue samples from small animals, with the goal of demonstrating improved contrast differentiation at low field strength coupled with reduced imaging times.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR005959-11
Application #
6348160
Study Section
Project Start
2000-09-01
Project End
2001-08-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
11
Fiscal Year
2000
Total Cost
$30,045
Indirect Cost
Name
Duke University
Department
Type
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
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