An apparatus has been built for the servo-control of workingcontractions of isolated frog skeletal muscle within an NMRspectrometer. 31P and 1H NMR spectra are obtained of repetitivelycontracting muscle. Recent effort has focused on identifying thetwo peaks which appear in the lactate methyl region of fatiguingmuscles. A variety of biochemical and NMR evidence has lead to theconclusion that both peaks are lactate, and that the lactate fromoxidative fibers is shifted by a susceptibility effect

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
2P41RR005964-06A1
Application #
5225180
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
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