This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. I am requesting the renewal of the grant MCB960010P with 10 Service units. The computer resources will be used for analysis of gene sequences as well as structual studies of RNA and protein molecules using the GCG software package. The project goals remain the same as last year and include the identification and analysis of mammalian testis genes that are regulated by cyclic AMP (cAMP) and the cyclic AMP response element binding protein (CREB
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