Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. In breast conservation surgery, the current method to locate non-palpable breast tumors is pre-operative image-guided wire placement localization. However, wire localization is unable to demarcate irregularly shaped tumors, and positive tumor margins, which require repeat surgeries, are discovered in many patients [1]. As an alternative to wire localization, we propose using MR-Image guided High Intensity Focused Ultrasound (MRgHIFU) to create thermal lesions which circumscribe a non-palpable breast tumor, providing an excision guide during breast conservation surgery. This study investigates visibility and palpability of HIFU lesions in cadaver breast tissue.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR009784-17
Application #
8362962
Study Section
Special Emphasis Panel (ZRG1-SBIB-U (40))
Project Start
2011-04-01
Project End
2012-03-31
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
17
Fiscal Year
2011
Total Cost
$13,020
Indirect Cost

  Institution

Name
Stanford University
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305

  Publications

Maclaren, Julian; Aksoy, Murat; Ooi, Melvyn B et al. (2018) Prospective motion correction using coil-mounted cameras: Cross-calibration considerations. Magn Reson Med 79:1911-1921
Guo, Jia; Holdsworth, Samantha J; Fan, Audrey P et al. (2018) Comparing accuracy and reproducibility of sequential and Hadamard-encoded multidelay pseudocontinuous arterial spin labeling for measuring cerebral blood flow and arterial transit time in healthy subjects: A simulation and in vivo study. J Magn Reson Imaging 47:1119-1132
Tamir, Jonathan I; Uecker, Martin; Chen, Weitian et al. (2017) T2 shuffling: Sharp, multicontrast, volumetric fast spin-echo imaging. Magn Reson Med 77:180-195
Lai, Lillian M; Cheng, Joseph Y; Alley, Marcus T et al. (2017) Feasibility of ferumoxytol-enhanced neonatal and young infant cardiac MRI without general anesthesia. J Magn Reson Imaging 45:1407-1418
Taviani, Valentina; Alley, Marcus T; Banerjee, Suchandrima et al. (2017) High-resolution diffusion-weighted imaging of the breast with multiband 2D radiofrequency pulses and a generalized parallel imaging reconstruction. Magn Reson Med 77:209-220
Uecker, Martin; Lustig, Michael (2017) Estimating absolute-phase maps using ESPIRiT and virtual conjugate coils. Magn Reson Med 77:1201-1207
Kogan, Feliks; Hargreaves, Brian A; Gold, Garry E (2017) Volumetric multislice gagCEST imaging of articular cartilage: Optimization and comparison with T1rho. Magn Reson Med 77:1134-1141
Aksoy, Murat; Maclaren, Julian; Bammer, Roland (2017) Prospective motion correction for 3D pseudo-continuous arterial spin labeling using an external optical tracking system. Magn Reson Imaging 39:44-52
Bian, W; Tranvinh, E; Tourdias, T et al. (2016) In Vivo 7T MR Quantitative Susceptibility Mapping Reveals Opposite Susceptibility Contrast between Cortical and White Matter Lesions in Multiple Sclerosis. AJNR Am J Neuroradiol 37:1808-1815
Vos, Sjoerd B; Aksoy, Murat; Han, Zhaoying et al. (2016) Trade-off between angular and spatial resolutions in in vivo fiber tractography. Neuroimage 129:117-132

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