This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. ABSTRACT: Training on laboratory instruments is provided for investigators at various stages of their professional careers, in addition to the resident postdoctoral fellows. R. Theberge is responsible for training on the Bruker Reflex IV MALDI reflectron TOF MS, M. J. C. Miller for the Bruker Esquire ion trap and U. Sommer, for the ESI Quattro II triple quadrupole LC/MS system. Under the direction of these senior personnel, new postdoctoral fellows, visiting scientists and graduate students have learned to operate the introductory level instruments and to process and interpret the resulting data. During this year two international guests came for yearlong stays to learn all aspects of mass spectral analysis of proteins and other biomacromolecules: Ms. Jawon Seo, a graduate student at Ewha Women's University in Seoul, Korea, and Francesca Lavatelli, MD, from the Univ. of Pavia, Italy, who, upon her return, will take on responsibility for transthyretin analysis in samples obtained from familial amyloid patients at the hospital and ressearch center where she is employed.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR010888-10
Application #
7369235
Study Section
Special Emphasis Panel (ZRG1-BECM (03))
Project Start
2006-07-01
Project End
2007-06-30
Budget Start
2006-07-01
Budget End
2007-06-30
Support Year
10
Fiscal Year
2006
Total Cost
$4,796
Indirect Cost
Name
Boston University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
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Sethi, Manveen K; Zaia, Joseph (2017) Extracellular matrix proteomics in schizophrenia and Alzheimer's disease. Anal Bioanal Chem 409:379-394
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Yu, Xiang; Sargaeva, Nadezda P; Thompson, Christopher J et al. (2015) In-Source Decay Characterization of Isoaspartate and ?-Peptides. Int J Mass Spectrom 390:101-109
Steinhorn, Benjamin S; Loscalzo, Joseph; Michel, Thomas (2015) Nitroglycerin and Nitric Oxide--A Rondo of Themes in Cardiovascular Therapeutics. N Engl J Med 373:277-80

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