Abstract

Available data suggest that if energy expenditure (EE) is involved in the etiology of obesity, the component of interest is activity-related EE (AEE). However, most prior studies examining the role of EE did not ensure metabolically stable conditions, include controls, or distinguish subjects according to ethnicity or predisposition to obesity. This study proposes to longitudinally follow current participants in another study (""""""""Energy expenditure in Post-obese black and white women"""""""") for the next 5 years. 31P magnetic resonance spectroscopy is being used to access the ATP cost of force production associated with a controlled exercise task. Currently, we are ending the 1st year of acquiring data on this longitudinal follow-up project and are in the initial stages of compiling the first set of data. At this time, we have no data to report.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR011811-05
Application #
6480905
Study Section
Project Start
2001-08-01
Project End
2003-02-28
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
5
Fiscal Year
2001
Total Cost
$155,764
Indirect Cost

  Institution

Name
University of Alabama Birmingham
Department
Type
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Sirikul, Bovorn; Hunter, Gary R; Larson-Meyer, D Enette et al. (2007) Relationship between metabolic function and skeletal muscle fatigue during a 90 s maximal isometric contraction. Appl Physiol Nutr Metab 32:394-9
Redden, David T; Divers, Jasmin; Vaughan, Laura Kelly et al. (2006) Regional admixture mapping and structured association testing: conceptual unification and an extensible general linear model. PLoS Genet 2:e137
Elgavish, Rotem A; Twieg, Donald B (2003) Improved depiction of small anatomic structures in MR images using Gaussian-weighted spirals and zero-filled interpolation. Magn Reson Imaging 21:103-12
Twieg, Donald B (2003) Parsing local signal evolution directly from a single-shot MRI signal: a new approach for fMRI. Magn Reson Med 50:1043-52
Larson-Meyer, D Enette; Newcomer, Bradley R; Hunter, Gary R (2002) Influence of endurance running and recovery diet on intramyocellular lipid content in women: a 1H NMR study. Am J Physiol Endocrinol Metab 282:E95-E106
Newcomer, B R; Larson-Meyer, D E; Hunter, G R et al. (2001) Skeletal muscle metabolism in overweight and post-overweight women: an isometric exercise study using (31)P magnetic resonance spectroscopy. Int J Obes Relat Metab Disord 25:1309-15
Newman, S D; Twieg, D B; Carpenter, P A (2001) Baseline conditions and subtractive logic in neuroimaging. Hum Brain Mapp 14:228-35
Newman, S D; Twieg, D (2001) Differences in auditory processing of words and pseudowords: an fMRI study. Hum Brain Mapp 14:39-47
Patton, H K; Chu, W J; Hetherington, H P et al. (2001) Alkaline pH changes in the cerebellum of asymptomatic HIV-infected individuals. NMR Biomed 14:12-8
Larson-Meyer, D E; Newcomer, B R; Hunter, G R et al. (2001) Relation between in vivo and in vitro measurements of skeletal muscle oxidative metabolism. Muscle Nerve 24:1665-76

Showing the most recent 10 out of 19 publications