This proposal describes our plans for the third renewal of the Center for Integrated Biomedical Computing (CIBC), hosted by the Scientific Computing and Imaging (SCI) Institute at the University of Utah. The CIBC is a research resource that produces open-source software tools for biomedical image-based modeling, biomedical simulation and estimation, and the visualization of biomedical data. The software tools created by the Center are supported by a critical mass of research in scientific computing housed within the SCI Institute. These software tools, the research that underlies them, and the driving biological projects and collaborations that motivate their development are unified by a single vision: to develop the role of image-based modeling and analysis in biomedical science and clinical practice. The overarching goal of this proposal is to advance the state of practice in biomedical computing and its applications both to biomedical science and to the translation of this science to clinical practice. We seek to achieve this goal by making advanced computation tools, tailored to the specific domains of image-based modeling, simulation, estimation, and visualization, accessible to scientists, engineers, and physicians by releasing readily usable, open-source software. We work closely with these users of our software, providing advice, technical support, workshops, and education to enhance their success with the tools we provide. Our long-term vision is to make scientific computing so useful and user friendly a tool that it becomes a transparent and ubiquitous aspect of clinical and scientific practice.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
3P41RR012553-12S1
Application #
8141546
Study Section
Special Emphasis Panel (ZRG1-BST-J (40))
Program Officer
Brazhnik, Olga
Project Start
2010-09-24
Project End
2011-09-23
Budget Start
2010-09-24
Budget End
2011-09-23
Support Year
12
Fiscal Year
2010
Total Cost
$647,286
Indirect Cost
Name
University of Utah
Department
Type
Organized Research Units
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Burton, B M; Aras, K K; Good, W W et al. (2018) Image-based modeling of acute myocardial ischemia using experimentally derived ischemic zone source representations. J Electrocardiol 51:725-733
Tong, Xin; Edwards, John; Chen, Chun-Ming et al. (2016) View-Dependent Streamline Deformation and Exploration. IEEE Trans Vis Comput Graph 22:1788-801
Burton, Brett M; Tate, Jess D; Good, Wilson et al. (2016) The Role of Reduced Left Ventricular, Systolic Blood Volumes in ST Segment Potentials Overlying Diseased Tissue of the Ischemic Heart. Comput Cardiol (2010) 43:209-212
Erem, Burak; Martinez Orellana, Ramon; Hyde, Damon E et al. (2016) Extensions to a manifold learning framework for time-series analysis on dynamic manifolds in bioelectric signals. Phys Rev E 93:042218
Raj, Mukund; Mirzargar, Mahsa; Preston, J Samuel et al. (2016) Evaluating Shape Alignment via Ensemble Visualization. IEEE Comput Graph Appl 36:60-71
Gao, Yi; Zhu, Liangjia; Cates, Joshua et al. (2015) A Kalman Filtering Perspective for Multiatlas Segmentation. SIAM J Imaging Sci 8:1007-1029
Gillette, Karli; Tate, Jess; Kindall, Brianna et al. (2015) Generation of Combined-Modality Tetrahedral Meshes. Comput Cardiol (2010) 2015:953-956
Erem, B; Hyde, D E; Peters, J M et al. (2015) COMBINED DELAY AND GRAPH EMBEDDING OF EPILEPTIC DISCHARGES IN EEG REVEALS COMPLEX AND RECURRENT NONLINEAR DYNAMICS. Proc IEEE Int Symp Biomed Imaging 2015:347-350
Coll-Font, J; Erem, B; Štóví?ek, P et al. (2015) A STATISTICAL APPROACH TO INCORPORATE MULTIPLE ECG OR EEG RECORDINGS WITH ARTIFACTUAL VARIABILITY INTO INVERSE SOLUTIONS. Proc IEEE Int Symp Biomed Imaging 2015:1053-1056
Coll-Font, Jaume; Burton, Brett M; Tate, Jess D et al. (2014) New Additions to the Toolkit for Forward/Inverse Problems in Electrocardiography within the SCIRun Problem Solving Environment. Comput Cardiol (2010) 2014:213-216

Showing the most recent 10 out of 149 publications