Abstract

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Impaired heart rate recovery immediately after exercise has been reported to be an important, independent marker of risk. However, the optimal measures of heart rate recovery have not been determined. We are systematically comparing the ability of conventional and newer dynamical measures of heart rate recovery in different groups of subjects with heart disease as well as healthy controls. The first investigation in this project involves analysis of exercise test data from subjects with congestive heart failure in a trial of pyridostigmine, a drug which increases vagal tone. This collaborative work is supported in part by the American Heart Association, the NHLBI and the NCRR/GCRC.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR013622-07
Application #
7366514
Study Section
Special Emphasis Panel (ZRG1-SBIB-H (40))
Project Start
2006-03-01
Project End
2007-02-28
Budget Start
2006-03-01
Budget End
2007-02-28
Support Year
7
Fiscal Year
2006
Total Cost
$8,085
Indirect Cost

  Institution

Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02215

  Publications

Clifford, Gari D; Silva, Ikaro; Moody, Benjamin et al. (2016) False alarm reduction in critical care. Physiol Meas 37:E5-E23
Burykin, Anton; Mariani, Sara; Henriques, Teresa et al. (2015) Remembrance of time series past: simple chromatic method for visualizing trends in biomedical signals. Physiol Meas 36:N95-102
Thomas, Robert Joseph; Mietus, Joseph E; Peng, Chung-Kang et al. (2014) Relationship between delta power and the electrocardiogram-derived cardiopulmonary spectrogram: possible implications for assessing the effectiveness of sleep. Sleep Med 15:125-31
Giladi, Nir; Horak, Fay B; Hausdorff, Jeffrey M (2013) Classification of gait disturbances: distinguishing between continuous and episodic changes. Mov Disord 28:1469-73
Maidan, Inbal; Plotnik, Meir; Mirelman, Anat et al. (2010) Heart rate changes during freezing of gait in patients with Parkinson's disease. Mov Disord 25:2346-54
Ivanov, Plamen Ch; Ma, Qianli D Y; Bartsch, Ronny P et al. (2009) Levels of complexity in scale-invariant neural signals. Phys Rev E Stat Nonlin Soft Matter Phys 79:041920
Herman, Talia; Inbar-Borovsky, Noit; Brozgol, Marina et al. (2009) The Dynamic Gait Index in healthy older adults: the role of stair climbing, fear of falling and gender. Gait Posture 29:237-41
Plotnik, M; Giladi, N; Hausdorff, J M (2009) Bilateral coordination of gait and Parkinson's disease: the effects of dual tasking. J Neurol Neurosurg Psychiatry 80:347-50
Hausdorff, Jeffrey M (2009) Gait dynamics in Parkinson's disease: common and distinct behavior among stride length, gait variability, and fractal-like scaling. Chaos 19:026113
Celi, Leo Anthony; Hinske, L Christian; Alterovitz, Gil et al. (2008) An artificial intelligence tool to predict fluid requirement in the intensive care unit: a proof-of-concept study. Crit Care 12:R151

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