This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The training of the next generation of biophysical scientists benefits from the availability of survey courses that introduce students to the variety of physical methods that can be utilized to address fundamental questions of biological significance. As part of the Biophysical Methods survey course offered by the Applied and Engineering Physics Department in the spring semester, Dr. Earle provided a week of lectures on ESR techniques and biological applications to students at Cornell University, both at the Ithaca campus, and at the Weill Medical College in New York City. Due to the collaborative nature of the course materials preparation, the presentation of the ESR material extended, enhanced and reinforced concepts introduced from previous presentations on, e.g., NMR allowing the students to assess the strengths of the various magnetic resonance techniques available to address questions arising in the study of biological systems. The course materials for the ESR lectures were given as a semi-animated PowerPoint presentation. They are available on the center web-site for visitor perusal.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biotechnology Resource Grants (P41)
Project #
5P41RR016292-10
Application #
8172095
Study Section
Special Emphasis Panel (ZRG1-BCMB-K (40))
Project Start
2010-09-01
Project End
2011-08-31
Budget Start
2010-09-01
Budget End
2011-08-31
Support Year
10
Fiscal Year
2010
Total Cost
$3,044
Indirect Cost
Name
Cornell University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
872612445
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Jain, Rinku; Vanamee, Eva S; Dzikovski, Boris G et al. (2014) An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ?. J Mol Biol 426:301-8
Pratt, Ashley J; Shin, David S; Merz, Gregory E et al. (2014) Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes. Proc Natl Acad Sci U S A 111:E4568-76
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Yu, Renyuan Pony; Darmon, Jonathan M; Hoyt, Jordan M et al. (2012) High-Activity Iron Catalysts for the Hydrogenation of Hindered, Unfunctionalized Alkenes. ACS Catal 2:1760-1764
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Dzikovski, Boris; Tipikin, Dmitriy; Freed, Jack (2012) Conformational distributions and hydrogen bonding in gel and frozen lipid bilayers: a high frequency spin-label ESR study. J Phys Chem B 116:6694-706

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