CORE D The overall objective of the Research Translation Core (Core D) is to oversee and execute the integration, dissemination and transfer of the scientific accomplishments emanating from the UC Davis Superfund Research Program (SRP) Center. The NIEHS SRP was created to address the need for innovative strategies and technologies to provide solutions to Superfund-related issues. As such, Core D will liaise between researchers within the UC Davis SRP and other National SRP Centers, as well as with the outside community, including other scientists, legislators and community partners to bridge the gap between the applied solutions needed for remediation of hazardous chemicals and the basic research performed in support of reducing the amount and toxicity of hazardous substances. Because progress toward solutions can be stunted without appropriate research translation tools and bi-directional partnerships to help shape and direct these tools, Core D will collaborate with all projects and cores to ensure that research products emanating from the UC Davis SRP are effectively transferred to and used by the appropriate end users. This will be achieved through communication within and external to the Center, building partnerships with government agencies, technology transfer, and the dissemination of relevant information to other end-users in a context applicable to the target audience. The expected outcome of the Core's activities is to facilitate the translation of UC Davis SRP technologies and research outcomes by involving relevant entities (e.g., intellectual property management, regulatory agencies, and partners) and assuring timely use of research products, which will ultimately help with the overall goal of NIEHS to protect human health from hazardous chemicals. This process starts with discovery, involves policy and ends with benefits to human populations and their environment. To achieve these overarching goals, the specific aims of the Research Translation Core are to I) translate research products to improve public and environmental health; II) communicate information about research products to relevant audiences and end-users within UC Davis, other SRP Centers, local, state and federal government, industry and the general public; and III) expand policy and community partnerships with local, state and federal government and regulatory agencies charged with protecting human health. To achieve these goals, the Research Translation Core will assure consistent communication with all projects and cores, build an advisory committee to help with all aspects of research translation, utilize several forms of media to translate UCD SRC research to appropriate end users, and host meetings to facilitate bi-directional communication and transdisciplinary research with external partners.

Public Health Relevance

CORE D The ability to communicate research findings and to facilitate the application of Superfund-related discoveries is critical to the Program. The myriad of strategies used in Core D reflects vast and diverse ability to reach broad audiences and create meaningful impacts aimed at improving public health. Through partnering with and delivering information to appropriate end-users (e.g., USEPA, ATSDR, Federal and local agencies and impacted communities), the UC Davis Research Translation Core is critical to the facility of the UC Davis Superfund Center to effectively use research to advance science and protect human and environmental health.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
5P42ES004699-32
Application #
9917781
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
32
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Napimoga, M H; Rocha, E P; Trindade-da-Silva, C A et al. (2018) Soluble epoxide hydrolase inhibitor promotes immunomodulation to inhibit bone resorption. J Periodontal Res 53:743-749
Blöcher, René; Wagner, Karen M; Gopireddy, Raghavender R et al. (2018) Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain. J Med Chem 61:3541-3550
Hao, Lei; Kearns, Jamie; Scott, Sheyenne et al. (2018) Indomethacin Enhances Brown Fat Activity. J Pharmacol Exp Ther 365:467-475
Yang, Yang-Ming; Sun, Dong; Kandhi, Sharath et al. (2018) Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation. Proc Natl Acad Sci U S A 115:613-618
Zheng, Jing; Chen, Juan; Zou, Xiaohan et al. (2018) Saikosaponin d causes apoptotic death of cultured neocortical neurons by increasing membrane permeability and elevating intracellular Ca2+ concentration. Neurotoxicology 70:112-121
Cui, Xiping; Vasylieva, Natalia; Shen, Ding et al. (2018) Biotinylated single-chain variable fragment-based enzyme-linked immunosorbent assay for glycocholic acid. Analyst 143:2057-2065
Harris, Todd R; Kodani, Sean; Rand, Amy A et al. (2018) Celecoxib Does Not Protect against Fibrosis and Inflammation in a Carbon Tetrachloride-Induced Model of Liver Injury. Mol Pharmacol 94:834-841
Bever, Candace S; Rand, Amy A; Nording, Malin et al. (2018) Effects of triclosan in breast milk on the infant fecal microbiome. Chemosphere 203:467-473
Zheng, Jing; McKinnie, Shaun M K; El Gamal, Abrahim et al. (2018) Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol 52:5469-5478
Lakkappa, Navya; Krishnamurthy, Praveen T; Yamjala, Karthik et al. (2018) Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development. J Pharm Biomed Anal 149:457-464

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