Abstract

application) ? ? This application requests the support of a symposium on the toxicity and leukemogenesis of benzene. Entitled Recent Advances in Benzene Toxicity, the symposium will focus on three areas of benzene toxicity: epidemiological studies on benzene-induced leukemia; biomarkers of exposure to benzene; and mechanisms of benzene-induced bone marrow damage. Epidemiological studies of people exposed to benzene have recently caused a re-evaluation of benzene-induced leukemia. This is an important time to re-examine key questions in human benzene toxicology in terms of both classical and molecular epidemiology. This symposium will provide an opportunity for researchers in the field to gather and discuss recent advances, synthesize current knowledge in the area and determine future directions for research. The proceedings will be published as a special issue of Chemico-Biological Interactions. ? ? ?

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Hazardous Substances Basic Research Grants Program (NIEHS) (P42)
Project #
3P42ES004705-18S1
Application #
6868446
Study Section
Special Emphasis Panel (ZES1-SET-A (S1))
Program Officer
Suk, William
Project Start
1997-04-01
Project End
2005-03-31
Budget Start
2004-06-04
Budget End
2005-03-31
Support Year
18
Fiscal Year
2004
Total Cost
$15,000
Indirect Cost

  Institution

Name
University of California Berkeley
Department
Type
Schools of Public Health
DUNS #
124726725
City
Berkeley
State
CA
Country
United States
Zip Code
94704

  Publications

Rappaport, Stephen M (2018) Redefining environmental exposure for disease etiology. NPJ Syst Biol Appl 4:30
Tachachartvanich, Phum; Sangsuwan, Rapeepat; Ruiz, Heather S et al. (2018) Assessment of the Endocrine-Disrupting Effects of Trichloroethylene and Its Metabolites Using in Vitro and in Silico Approaches. Environ Sci Technol 52:1542-1550
Guyton, Kathryn Z; Rieswijk, Linda; Wang, Amy et al. (2018) Key Characteristics Approach to Carcinogenic Hazard Identification. Chem Res Toxicol :
Roh, Taehyun; Steinmaus, Craig; Marshall, Guillermo et al. (2018) Age at Exposure to Arsenic in Water and Mortality 30-40 Years After Exposure Cessation. Am J Epidemiol 187:2297-2305
Daniels, Sarah I; Chambers, John C; Sanchez, Sylvia S et al. (2018) Elevated Levels of Organochlorine Pesticides in South Asian Immigrants Are Associated With an Increased Risk of Diabetes. J Endocr Soc 2:832-841
Guyton, Kathryn Z; Rusyn, Ivan; Chiu, Weihsueh A et al. (2018) Application of the key characteristics of carcinogens in cancer hazard identification. Carcinogenesis 39:614-622
Grigoryan, Hasmik; Edmands, William M B; Lan, Qing et al. (2018) Adductomic signatures of benzene exposure provide insights into cancer induction. Carcinogenesis 39:661-668
Barazesh, James M; Prasse, Carsten; Wenk, Jannis et al. (2018) Trace Element Removal in Distributed Drinking Water Treatment Systems by Cathodic H2O2 Production and UV Photolysis. Environ Sci Technol 52:195-204
Counihan, Jessica L; Wiggenhorn, Amanda L; Anderson, Kimberly E et al. (2018) Chemoproteomics-Enabled Covalent Ligand Screening Reveals ALDH3A1 as a Lung Cancer Therapy Target. ACS Chem Biol 13:1970-1977
Lavy, Adi; Keren, Ray; Yu, Ke et al. (2018) A novel Chromatiales bacterium is a potential sulfide oxidizer in multiple orders of marine sponges. Environ Microbiol 20:800-814

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